| Vacuum therapy in erectile dysfunction--science and clinical evidence. | |
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MedLine Citation:
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PMID: 20410903 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Vacuum therapy (VT) utilizes negative pressure to distend the corporal sinusoids and to increase the blood inflow to the penis. Depending on its purpose, VT could be used as vacuum constriction device (VCD), with the aid of an external constricting ring which is placed at the base of penis to prevent blood outflow, maintaining the erection for sexual intercourse. Also, as a vacuum erectile device (VED), without the application of a constriction ring, just increases blood oxygenation to the corpora cavernosa and for other purposes. The emerging of phosphodiesterase 5 inhibitors (PDE(5)I) for the treatment of erectile dysfunction (ED) eclipsed VCD as therapeutic choice for ED; however, widespread usage of VED as part of penile rehabilitation after radical prostatectomy and other purposes rekindle the interest for VT. The underlying hypothesis is that the artificial induction of erections shortly after surgery facilitates tissue oxygenation, reducing cavernosal fibrosis in the absence of nocturnal erections, and potentially increases the likelihood of preserving erectile function. Due to its ability to draw blood into the penis regardless of nerve disturbance, VED has become the centerpiece of penile rehabilitation protocols. Herein, we reviewed the history, mechanism, application, side effects and future direction of VT in ED. |
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Authors:
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J Yuan; A N Hoang; C A Romero; H Lin; Y Dai; R Wang |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-04-22 |
Journal Detail:
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Title: International journal of impotence research Volume: 22 ISSN: 1476-5489 ISO Abbreviation: Int. J. Impot. Res. Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-07-15 Completed Date: 2010-10-25 Revised Date: 2011-01-07 |
Medline Journal Info:
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Nlm Unique ID: 9007383 Medline TA: Int J Impot Res Country: England |
Other Details:
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Languages: eng Pagination: 211-9 Citation Subset: IM |
Affiliation:
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Division of Urology, University of Texas Medical School at Houston, Houston, TX 77030, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Coitus Erectile Dysfunction / therapy* Humans Male Penile Erection Penis / blood supply Phosphodiesterase 5 Inhibitors Phosphodiesterase Inhibitors / adverse effects, contraindications, therapeutic use Prostatectomy / rehabilitation Randomized Controlled Trials as Topic Vacuum Vasodilation |
| Chemical | |
Reg. No./Substance:
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0/Phosphodiesterase 5 Inhibitors; 0/Phosphodiesterase Inhibitors |
| Comments/Corrections | |
Erratum In:
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Int J Impot Res. 2010 Jul;22(4):290 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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