Document Detail


A VCD robust mode analysis of induced chirality: the case of pulegone in chloroform.
MedLine Citation:
PMID:  20049972     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Vibrational modes in an achiral molecule may acquire rotational strength by complexation to a chiral molecule, as happens for achiral solvent molecules complexed to a chiral solute. We investigate this transfer of chirality in vibrational circular dichroism for the pulegone molecule in CDCl(3) solvent from the point of view of the robustness concept introduced recently. It turns out that the transfer of chirality yields nonrobust modes, which means that, although they are observed in vibrational circular dichroism (VCD) experiments, the sign of these modes cannot be predicted reliably with standard (Density Functional Theory) VCD calculations. This limits the usefulness of the induced chirality phenomenon for obtaining information on the intermolecular interactions that give rise to it.
Authors:
Valentin Paul Nicu; Elke Debie; Wouter Herrebout; Benjamin Van der Veken; Patrick Bultinck; Evert Jan Baerends
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chirality     Volume:  21 Suppl 1     ISSN:  1520-636X     ISO Abbreviation:  Chirality     Publication Date:  2009  
Date Detail:
Created Date:  2010-02-08     Completed Date:  2010-05-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8914261     Medline TA:  Chirality     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E287-97     Citation Subset:  -    
Copyright Information:
(c) 2010 Wiley-Liss, Inc.
Affiliation:
Theoretical Chemistry, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. nicu@few.vu.nl
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mechanical versus pharmacologic support for cardiogenic shock.
Next Document:  Should fine-needle aspiration cytology be the first choice diagnostic modality for assessment of all...