Document Detail

Utilizing fractional resurfacing in the treatment of therapy-resistant melasma.
MedLine Citation:
PMID:  16020216     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Multiple treatment modalities have been employed for the management of melasma with minimal to no success. OBJECTIVE: We propose fractional resurfacing as a new treatment modality for melasma. METHODS: A 31-year-old Caucasian female with facial epidermal and dermal melasma, resistant to multiple courses of topical therapies, was treated with two sessions of full-face fractional resurfacing (Fraxel(TM) Laser; Reliant technologies, San Diego, CA), separated by a three-week interval. Clinical improvement was assessed by Wood's Lamp examination as well as parallel and cross-polarized comparative photography at baseline and 6 months later. RESULTS: Marked reduction in epidermal and dermal facial pigmentation was observed at the six-month follow-up visit. CONCLUSION: Fractional resurfacing may prove to be an effective and safe treatment modality for lightening of the epidermal and dermal pigmentation of melasma. Further studies with long-term follow-up periods and multiple patients with diverse skin phototypes and different variants of melasma are warranted.
Zeina S Tannous; Susanne Astner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology     Volume:  7     ISSN:  1476-4172     ISO Abbreviation:  J Cosmet Laser Ther     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-07-15     Completed Date:  2005-10-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101136419     Medline TA:  J Cosmet Laser Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  39-43     Citation Subset:  IM    
Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
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MeSH Terms
Dose Fractionation*
Facial Dermatoses / pathology,  radiotherapy*
Laser Therapy*
Melanosis / pathology,  radiotherapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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