| Utilizing fractional resurfacing in the treatment of therapy-resistant melasma. | |
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MedLine Citation:
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PMID: 16020216 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Multiple treatment modalities have been employed for the management of melasma with minimal to no success. OBJECTIVE: We propose fractional resurfacing as a new treatment modality for melasma. METHODS: A 31-year-old Caucasian female with facial epidermal and dermal melasma, resistant to multiple courses of topical therapies, was treated with two sessions of full-face fractional resurfacing (Fraxel(TM) Laser; Reliant technologies, San Diego, CA), separated by a three-week interval. Clinical improvement was assessed by Wood's Lamp examination as well as parallel and cross-polarized comparative photography at baseline and 6 months later. RESULTS: Marked reduction in epidermal and dermal facial pigmentation was observed at the six-month follow-up visit. CONCLUSION: Fractional resurfacing may prove to be an effective and safe treatment modality for lightening of the epidermal and dermal pigmentation of melasma. Further studies with long-term follow-up periods and multiple patients with diverse skin phototypes and different variants of melasma are warranted. |
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Authors:
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Zeina S Tannous; Susanne Astner |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology Volume: 7 ISSN: 1476-4172 ISO Abbreviation: J Cosmet Laser Ther Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-07-15 Completed Date: 2005-10-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101136419 Medline TA: J Cosmet Laser Ther Country: England |
Other Details:
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Languages: eng Pagination: 39-43 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. ztannous@partners.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Dose Fractionation* Facial Dermatoses / pathology, radiotherapy* Female Humans Laser Therapy* Melanosis / pathology, radiotherapy* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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