| Utilization of supplemental iron by premature infants fed fortified human milk. | |
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MedLine Citation:
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PMID: 10447137 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We measured red blood cell iron incorporation (RBC-inc) in 13 human milk-fed premature infants (birthweight 1037 +/- 289 g, gestational age 27 +/- 2 wk, weight at start of study 1571 +/- 426 g) who were receiving full tube-feedings of human milk fortified with a commercial human milk fortifier (FortHM). The relative RBC-inc of supplemental iron (2 mg/kg/d of ferrous sulfate) was assessed using 57Fe sulfate mixed directly into a 24-h volume of FortHM, and 54Fe sulfate given as a bolus between two FortHM feedings the next day. RBC-inc was similar between the two methods of supplemental iron administration (4.7 +/- 2.5% vs 4.6 +/- 1.5%, respectively). Although these values are lower than RBC-inc expected from iron native to human milk, the relatively large amount of iron in the supplements contributed most of the iron incorporated into RBC by the infants. There was a significant positive correlation between the reticulocyte count and RBC-inc. As the high nutrient (especially calcium) content of the FortHM did not interfere with iron utilization, adding iron directly to FortHM, or incorporating it into commercial fortifiers, may be a practical method to provide iron to premature infants. |
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Authors:
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G J Moody; R J Schanler; S A Abrams |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: 88 ISSN: 0803-5253 ISO Abbreviation: Acta Paediatr. Publication Date: 1999 Jul |
Date Detail:
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Created Date: 1999-10-21 Completed Date: 1999-10-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: NORWAY |
Other Details:
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Languages: eng Pagination: 763-7 Citation Subset: IM |
Affiliation:
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USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston 77030, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Weight Energy Intake Erythrocyte Count Food, Fortified* Humans Infant, Newborn Infant, Premature Iron, Dietary* Milk, Human* |
| Grant Support | |
ID/Acronym/Agency:
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M0-1-RR-00188/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Iron, Dietary |
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