Document Detail


Utilization of glycoprotein IIb/IIIa inhibitors in non-ST-elevation acute myocardial infarction in a tertiary referral medical center in a developing country.
MedLine Citation:
PMID:  16581145     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We analyze the patterns of utilization of glycoprotein (GP) IIb/IIIa inhibitors in patients with non-ST-elevation myocardial infarction (NSTEMI) in a tertiary medical center in a developing country and we compare it to data from the national registry of myocardial infarction 4 (NRMI 4) in the USA. GP IIb/IIIa inhibitors were used in 28% of patients. The significant multivariate predictors of GP IIb/IIIa inhibitors utilization were Age <70 years (p=0.05), TIMI score > or =4 (p=0.002), and the absence of congestive heart failure (p=0.01) or prior infarction (p=0.04). Our results show striking similarity to what has been reported by the NRMI 4 registry, in terms of the overall underutilization of GP IIb/IIIa inhibitors in NSTEMI patients, and particularly in elderly patients and women. These findings underscore the importance of initiating a worldwide campaign to educate physicians about the pivotal role of GP IIb/IIIa inhibitors in the management of patients with NSTEMI.
Authors:
Mouhamad Abdallah; Wassef Karrowni; Habib A Dakik
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Publication Detail:
Type:  Letter     Date:  2006-04-03
Journal Detail:
Title:  International journal of cardiology     Volume:  114     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-11-27     Completed Date:  2007-01-25     Revised Date:  2007-02-22    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  282-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Electrocardiography
Female
Humans
Male
Myocardial Infarction / drug therapy*,  physiopathology
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
Referral and Consultation
Retrospective Studies
Chemical
Reg. No./Substance:
0/Platelet Glycoprotein GPIIb-IIIa Complex

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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