| Utilization of dietary nucleic acid purines for nucleotide and nucleic acid synthesis in the mouse. | |
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MedLine Citation:
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PMID: 776369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three preparations of radioactive yeast nucleic acids were fed to mice. One was labeled predominantly in the guanine moiety, one was labeled predominantly in the adenine moiety, and in one adenine and guanine were labeled equally. Most of the nucleic acid purines produced by digestion were excreted in the urine. However, a small amount was utilized for nucleotide and nucleic acid synthesis in the mouse tissues. Small intestine, liver and skeletal muscle contained most of the purines that were retained in the tissues. Dietary nucleic acid adenine appeared to be utilized somewhat more efficiently than was dietary nucleic acid guanine. |
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Authors:
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P W Burridge; R A Woods; J F Henderson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Canadian journal of biochemistry Volume: 54 ISSN: 0008-4018 ISO Abbreviation: Can. J. Biochem. Publication Date: 1976 May |
Date Detail:
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Created Date: 1976-09-01 Completed Date: 1976-09-01 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0421034 Medline TA: Can J Biochem Country: CANADA |
Other Details:
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Languages: eng Pagination: 500-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenine
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metabolism Administration, Oral Animals DNA / administration & dosage, biosynthesis, metabolism* Female Guanine / metabolism Intestine, Small / metabolism Kinetics Liver / metabolism Mice Mice, Inbred ICR Muscles / metabolism Organ Specificity Purines / biosynthesis* RNA / administration & dosage, biosynthesis, metabolism* Saccharomyces cerevisiae |
| Chemical | |
Reg. No./Substance:
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0/Purines; 63231-63-0/RNA; 73-24-5/Adenine; 73-40-5/Guanine; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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