Document Detail


Utilization of cystine by dermatophytes on glucose-peptone media.
MedLine Citation:
PMID:  3397007     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
All the 16 strains of dermatophytes tested here metabolized cystine (3 mmol/L) in two glucose-peptone media with a different C: N ratio. Cystine was utilized as a sulfur source and, in addition, as a carbon and nitrogen source, in parallel with growth. Excess sulfur was excreted to the medium after its oxidation as inorganic sulfate and sulfite. In a physiologically alkaline medium the growth was fast and was accompanied by a pH increase and cystine was utilized intensively. Eleven species used up all cystine available. Sulfate was the main oxidation product, sulfite was produced at a low concentration, at the beginning of growth in particular. Only traces of thiol compounds (cysteine) were present in the medium. In a physiologically acid medium growth was soon limited by a decreased pH (below 5.0) but cystine continued to be utilized at an identical rate. All cystine was used up by 5 species. The tendency to produce sulfite in addition to sulfate further increased and sulfite was often the predominant product. Concentrations of thiol compounds were also substantially higher. Thus, dermatophytes can utilize cystine even under conditions that do not support good growth and increase the sulfite production.
Authors:
J Kunert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Folia microbiologica     Volume:  33     ISSN:  0015-5632     ISO Abbreviation:  Folia Microbiol. (Praha)     Publication Date:  1988  
Date Detail:
Created Date:  1988-09-02     Completed Date:  1988-09-02     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0376757     Medline TA:  Folia Microbiol (Praha)     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  188-97     Citation Subset:  IM    
Affiliation:
Department of Biology, Medical Faculty, Palacký University, Olomouc, Czechoslovakia.
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MeSH Terms
Descriptor/Qualifier:
Arthrodermataceae / growth & development,  metabolism*
Culture Media
Cystine / metabolism*
Hydrogen-Ion Concentration
Oxidation-Reduction
Sulfates / metabolism
Sulfites / metabolism
Chemical
Reg. No./Substance:
0/Culture Media; 0/Sulfates; 0/Sulfites; 56-89-3/Cystine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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