Document Detail


Utilization of intraoperative motor mapping in glioma surgery with high-field intraoperative magnetic resonance imaging.
MedLine Citation:
PMID:  20733348     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND/AIMS: The main goal of glioma surgery is to maximize tumor resection while minimizing neurologic injury. The use of high-field intraoperative magnetic resonance imaging (iMRI) and intraoperative cortical mapping (IOM) together enable the surgeon to increase the extent of tumor resection (EOR) and preserve the neurological function. However, there is insufficient evidence to validate the use of IOM with high-field iMRI.
METHODS: To study the safety and utility of IOM in a high-field (1.5 T) iMRI suite, we retrospectively studied 38 patients with glioma who underwent surgery with IOM in the iMRI suite.
RESULTS: We were able to use IOM in the iMRI suite without any adverse side effects or difficulty. Median EOR was 97%. A new or worsening motor deficit occurred in 14 (37%) patients immediately after the surgery, with 3 (8%) patients exhibiting persistent deficit at 6 months.
CONCLUSION: Our findings suggest that IOM can be successfully used in a high-field MRI environment and can help minimize postoperative motor deficit with a higher EOR.
Authors:
Mustafa Aziz Hatiboglu; Jeffrey S Weinberg; Dima Suki; Sudhakar Tummala; Ganesh Rao; Raymond Sawaya; Sujit S Prabhu
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Publication Detail:
Type:  Journal Article     Date:  2010-08-21
Journal Detail:
Title:  Stereotactic and functional neurosurgery     Volume:  88     ISSN:  1423-0372     ISO Abbreviation:  Stereotact Funct Neurosurg     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902881     Medline TA:  Stereotact Funct Neurosurg     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  345-52     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 S. Karger AG, Basel.
Affiliation:
Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, Houston, Tex. 77030, USA.
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