Document Detail


The utilization of gum tragacanth to improve the growth of Rhodotorula aurantiaca and the production of gamma-decalactone in large scale.
MedLine Citation:
PMID:  19680818     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The production of gamma-decalactone and 4-hydroxydecanoic acid by the psychrophilic yeast R. aurantiaca was studied. The effect of both compounds on the growth of R. aurantiaca was also investigated and our results show that gamma-decalactone must be one of the limiting factors for its production. The addition of gum tragacanth to the medium at concentrations of 3 and 4 g/l seems to be an adequate strategy to enhance gamma-decalactone production and to reduce its toxicity towards the cell. The production of gamma-decalactone and 4-hydroxydecanoic acid was significantly higher in 20-l bioreactor than in 100-l bioreactor. By using 20 g/l of castor oil, 6.5 and 4.5 g/l of gamma-decalactone were extracted after acidification at pH 2.0 and distillation at 100 degrees C for 45 min in 20- and 100-l bioreactors, respectively. We propose a process at industrial scale using a psychrophilic yeast to produce naturally gamma-decalactone from castor oil which acts also as a detoxifying agent; moreover the process was improved by adding a natural gum.
Authors:
Mohamed Alchihab; Jacqueline Destain; Mario Aguedo; Jean-Paul Wathelet; Philippe Thonart
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-13
Journal Detail:
Title:  Applied biochemistry and biotechnology     Volume:  162     ISSN:  1559-0291     ISO Abbreviation:  Appl. Biochem. Biotechnol.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-04-02     Completed Date:  2010-07-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8208561     Medline TA:  Appl Biochem Biotechnol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  233-41     Citation Subset:  IM    
Affiliation:
Faculté Universitaire des Sciences Agronomiques de Gembloux, Centre Wallon de Biologie Industrielle, Unité de Bio-industries, Passage des Déportés, 2, 5030 Gembloux, Belgium. alchihab.m@fsagx.ac.be
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MeSH Terms
Descriptor/Qualifier:
Bioreactors
Decanoates / metabolism*,  toxicity
Gum Arabic / pharmacology
Lactones / metabolism*,  toxicity
Polysaccharides, Bacterial / pharmacology
Rhodotorula / drug effects*,  growth & development*,  metabolism
Surface-Active Agents / pharmacology*
Tragacanth / pharmacology*
Chemical
Reg. No./Substance:
0/4-hydroxydecanoic acid; 0/Decanoates; 0/Lactones; 0/Polysaccharides, Bacterial; 0/Surface-Active Agents; 11138-66-2/xanthan gum; 706-14-9/decan-4-olide; 9000-01-5/Gum Arabic; 9000-65-1/Tragacanth

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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