Document Detail

Utilization of GnRH agonists for poor responders in an IVF programme.
MedLine Citation:
PMID:  2496139     Owner:  NLM     Status:  MEDLINE    
Thirty-four patients in whom conventional ovarian stimulation had previously failed twice due to low levels of oestradiol, received ovarian stimulation by pure FSH for 5 days, followed by a combination of FSH and HMG, after a preliminary period of pituitary de-sensitization with LHRH agonist. Oocytes were recovered from 33 patients and 28 embryos replaced, 10 became pregnant and eight pregnancies were ongoing and resulted in the birth of 13 healthy babies. This ongoing pregnancy rate of 23.5% per treatment cycle is identical to that reported for normally responding patients. The use of LHRH agonists in so-called poor responders is of obvious interest.
J Belaisch-Allart; J Testart; R Frydman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  4     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-06-02     Completed Date:  1989-06-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  33-4     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Hospital A., Béclère, Clamart, France.
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MeSH Terms
Buserelin / pharmacology*
Chorionic Gonadotropin / pharmacology
Fertilization in Vitro*
Follicle Stimulating Hormone / pharmacology
Menotropins / pharmacology
Ovary / drug effects*
Reg. No./Substance:
0/Chorionic Gonadotropin; 57982-77-1/Buserelin; 61489-71-2/Menotropins; 9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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