| Utility of whole gut transit scintigraphy in patients with chronic gastrointestinal symptoms. | |
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MedLine Citation:
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PMID: 20072076 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To review our experience of doing whole gut transit scintigraphy in patients presenting with functional gastrointestinal problems and to determine its clinical usefulness. METHOD: All whole gut transit studies using a liquid meal over a 5-year-period were reviewed and clinical outcome assessed. RESULTS: Fifty-five patients (44 women; mean age 43 years) underwent whole gut transit scintigraphy using indium-111 diethylene triamine penta-acetic acid in water. The main symptoms were constipation (49%), dyspepsia (25%) and diarrhoea (25%). Colonic transit was delayed in 63% of patients with constipation, which was significantly (P=0.005) higher than that in patients with dyspepsia. Delayed colonic transit was also seen in 43% of patients with diarrhoea. Only 26% of patients with constipation had a delay in liquid gastric emptying and small bowel transit. Gastric emptying, small bowel transit and colonic transit were normal in 43, 79 and 29% of patients with dyspepsia, respectively. There was no statically significant difference in gastric emptying and small bowel transit between patients with constipation, diarrhoea and dyspepsia. CONCLUSION: Liquid-phase whole gut transit scintigraphy seems to be a useful investigation in patients with chronic gastrointestinal symptoms. Rational use of this modality may help the clinician change the management or better characterize the underlying problem/diagnosis in the majority of patients with functional symptoms. |
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Authors:
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Kottekkattu Balan; Lankanatha Alwis; Luke Ienari Sonoda; Davina Pawaroo; David R Parry-Jones; Stephen Middleton |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 31 ISSN: 1473-5628 ISO Abbreviation: Nucl Med Commun Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-08 Completed Date: 2010-07-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: England |
Other Details:
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Languages: eng Pagination: 328-33 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chronic Disease Female Gastrointestinal Diseases / radionuclide imaging*, therapy Gastrointestinal Tract / radionuclide imaging* Humans Male Radionuclide Imaging / methods* Retrospective Studies |
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