Document Detail


Utility of temporally-extended signal space separation algorithm for magnetic noise from vagal nerve stimulators.
MedLine Citation:
PMID:  22727713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the utility of a temporally-extended signal space separation algorithm (tSSS) for patients with vagal nerve stimulator (VNS).
METHODS: We evaluated median nerve somatosensory evoked responses (SER) of magnetoencephalography (MEG) in 27 VNS patients (48 sides) with/without tSSS processing. We classified SER dipoles as 'acceptable' if: (A) the location of the dipole was in the expected location in the central sulcus, and (B) the goodness of fit value (GOF) was greater than 80%. We evaluated (1) the number of sides which produced acceptable dipoles in each dataset (i.e. with/without tSSS processing), and in cases where the both data produced reliable dipoles, (2) compared their GOFs and the 95% confidence volumes (CV) (mm(3)). Statistical differences in the GOF and CV between with/without tSSS conditions were determined by paired t test.
RESULTS: Only 11 (23%) responses had reliable dipoles without tSSS processing, while all 48 (100%) had acceptable dipoles under tSSS processing. Additionally, the latter group had significantly higher GOF (increased by 7% on average) and lower CV (mean decrease of 200 mm(3)) than the former (p<0.01).
CONCLUSIONS: Processing with tSSS quantitatively improves dipole fitting of known sources in VNS patients.
SIGNIFICANCE: This algorithm permits satisfactory MEG testing in the relatively commonly encountered epilepsy patient with VNS.
Authors:
Yosuke Kakisaka; John C Mosher; Zhong I Wang; Kazutaka Jin; Anne-Sophie Dubarry; Andreas V Alexopoulos; Richard C Burgess
Related Documents :
9130743 - The chromosomal normality of unfertilized oocytes from patients with polycystic ovarian...
22473263 - Multiple sclerosis in oman.
1485593 - Cellular immunity in paracoccidioidomycosis.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-06-23
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  124     ISSN:  1872-8952     ISO Abbreviation:  Clin Neurophysiol     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-10     Completed Date:  2013-08-07     Revised Date:  2014-07-01    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1277-82     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age of Onset
Algorithms*
Brain Mapping
Child
Epilepsy / therapy*
Evoked Potentials, Somatosensory / physiology*
Female
Functional Laterality
Humans
Magnetoencephalography
Male
Middle Aged
Neural Conduction / physiology
Noise*
Signal Processing, Computer-Assisted*
Vagus Nerve Stimulation / methods*
Young Adult
Grant Support
ID/Acronym/Agency:
R01 EB009048/EB/NIBIB NIH HHS; R01 NS074980/NS/NINDS NIH HHS; R01-EB009048/EB/NIBIB NIH HHS; R01-NS074980/NS/NINDS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparison of polysomnographic data in age-, sex- and Axis I psychiatric diagnosis matched HIV-serop...
Next Document:  More excited for negative facial expressions in depression: Evidence from an event-related potential...