| Utility of sepsis evaluation in infants 90 days of age or younger with fever and clinical bronchiolitis. | |
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MedLine Citation:
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PMID: 14688564 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To identify the clinical utility of obtaining blood, urine and cerebrospinal fluid for bacterial culture among febrile infants <90 days of age with clinical bronchiolitis. DESIGN: Retrospective chart review from 1995 to 2000. SETTING: Urban emergency department of a tertiary children's hospital. PARTICIPANTS: All infants <90 days of age presenting with fever and clinical bronchiolitis. MAIN OUTCOME MEASURES: Result of the cultures of blood, urine and cerebrospinal fluid. RESULTS: Of 3051 (11%) febrile infants, 329 met criteria for clinical bronchiolitis. Blood for culture was obtained from 309 (94%), urine for culture was obtained from 273 (83%) and cerebrospinal fluid for culture was obtained from 200 (61%). One hundred eighty-seven (57%) infants had all 3 specimens sent for culture. No cases of bacteremia [0%; 95% confidence interval (CI), 0, 1.1%] or meningitis (0%; 95% CI 0, 1.8%) occurred among these infants. However, 6 infants (2%; 95% CI 0.8, 5.7%), all male, had a culture of urine consistent with infection (4 Escherichia coli, 1 Staphylococcus aureus, 1 viridans streptococci). CONCLUSION: The risk of bacteremia or meningitis among infants <90 days with fever and bronchiolitis is low in this age group. The risk of urinary tract infection in this age group is also low, but not negligible, at 2%. |
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Authors:
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Elliot Melendez; Marvin B Harper |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Pediatric infectious disease journal Volume: 22 ISSN: 0891-3668 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2003-12-22 Completed Date: 2004-02-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: United States |
Other Details:
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Languages: eng Pagination: 1053-6 Citation Subset: IM |
Affiliation:
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Department of Medicine, Children's Hospital Boston, MA 02115, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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administration & dosage Bacteremia / drug therapy, epidemiology*, microbiology* Blood / microbiology Bronchiolitis / drug therapy, epidemiology*, microbiology* Cross-Sectional Studies Emergency Service, Hospital Female Fever / diagnosis, drug therapy, epidemiology* Follow-Up Studies Humans Infant Infant, Newborn Male Microbial Sensitivity Tests Retrospective Studies Risk Assessment Severity of Illness Index Treatment Outcome Urban Population Urinalysis Urine / microbiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
| Comments/Corrections | |
Comment In:
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Pediatr Infect Dis J. 2004 Apr;23(4):376-7; author reply 377
[PMID:
15071307
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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