Document Detail


Utility of sentinel node biopsy in vulvar and vaginal melanoma: report of two cases and review of the literature.
MedLine Citation:
PMID:  17343569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sentinel node (SN) biopsy is widely applied for treatment planning of cutaneous melanoma. However, using this strategy in female lower genital tract tumors has not yet been established. We report two cases, one each of vulvar and vaginal melanoma who underwent SN biopsy and review the available literature. Our experience and available limited evidence suggests that this low morbidity technique can be used for obtaining prognostic information and hence treatment planning for this disease. However, a false negative rate perhaps in the order of 15% suggests that careful consideration is necessary before using sentinel lymph node biopsy in the management of vulvar and vaginal melanoma.
Authors:
K K Dhar; N DAS; D A Brinkman; J L Beynon; R P Woolas
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Publication Detail:
Type:  Case Reports; Evaluation Studies; Journal Article; Review     Date:  2007-03-02
Journal Detail:
Title:  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society     Volume:  17     ISSN:  1048-891X     ISO Abbreviation:  Int. J. Gynecol. Cancer     Publication Date:    2007 May-Jun
Date Detail:
Created Date:  2007-05-16     Completed Date:  2007-08-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111626     Medline TA:  Int J Gynecol Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  720-3     Citation Subset:  IM    
Affiliation:
Department of Gynaecological Oncology, Saint Mary's Hospital, Portsmouth, United Kingdom. kdhar2002@yahoo.co.uk
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Humans
Melanoma / diagnosis*,  pathology
Prognosis
Sentinel Lymph Node Biopsy / methods*
Vaginal Neoplasms / diagnosis*,  pathology
Vulvar Neoplasms / diagnosis*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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