| Utility of pulsed Doppler in the diagnosis and follow-up of acute vascular graft rejection treated with OKT3 monoclonal antibody or antilymphocyte serum. | |
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MedLine Citation:
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PMID: 1900963 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fifteen patients with severe acute vascular graft rejection (twelve of them steroid-resistant) treated with OKT3 monoclonal antibody (8) or antilymphocyte serum (7) were sequentially studied with duplex-Doppler ultrasonography (DDUS). Measurements of intrarenal resistance were obtained by means of the resistive index (RI). During rejection episodes, the intrarenal resistance was increased in all patients (RI range: 0.89-1), with absent or reversed diastolic blood flow. Normalization of diastolic blood flow was documented prior to the decrease of serum creatinine level in all patients who recovered from a rejection episode. We conclude that DDUS is a noninvasive technique useful in the diagnosis and monitoring of acute vascular graft rejection. Prediction of graft outcome after rejection treatment could probably be made based on DDUS findings. |
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Authors:
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R Gilabert; J M Campistol; C Bru; J Vilardell; L Bianchi; J Andreu |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Transplantation Volume: 51 ISSN: 0041-1337 ISO Abbreviation: Transplantation Publication Date: 1991 Mar |
Date Detail:
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Created Date: 1991-04-24 Completed Date: 1991-04-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0132144 Medline TA: Transplantation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 614-8 Citation Subset: IM |
Affiliation:
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Renal Transplant Unit, Hospital Clinic i Provincial, University of Barcelona, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Monoclonal / therapeutic use* Antilymphocyte Serum / therapeutic use* Biopsy, Needle Creatinine / blood Female Graft Rejection* Humans Immunosuppression Kidney / ultrasonography Kidney Transplantation / immunology*, pathology Male Muromonab-CD3 Renal Circulation Ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Antilymphocyte Serum; 0/Muromonab-CD3; 60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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