Document Detail


Utility of the cutaneous silent period in patients with diabetes mellitus.
MedLine Citation:
PMID:  20417526     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We performed this study to evaluate whether or not the cutaneous silent period (CSP) is a useful metric to identify small-fiber neuropathy in diabetic patients. The CSP was measured from the abductor pollicis brevis muscle in 30 healthy controls and 110 diabetic patients, who in turn were divided into 3 subgroups (patients with large-fiber neuropathy, patients with small-fiber neuropathy, and asymptomatic patients). The measured CSP and clinical characteristics were compared among the groups. The power of the CSP in discriminating patients from controls and any correlation with other clinical variables were analyzed. Each patient subgroup had a significantly delayed CSP latency compared to the controls. The latency of patients with large-fiber neuropathy was also significantly prolonged compared to the other subgroups of patients. The CSP latency was the only variable to discriminate patients. The latency showed a significant correlation with the late responses in nerve conduction studies. Thus, the CSP latency may be a useful tool in evaluating small neural fiber function in diabetic patients.
Authors:
Byung-Jo Kim; Nan-Hee Kim; Sin Gon Kim; Hakjae Roh; Ha-Rim Park; Moon-Ho Park; Kun-Woo Park; S Charles Cho; Yuen T So
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Publication Detail:
Type:  Historical Article; Journal Article     Date:  2010-04-24
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  293     ISSN:  1878-5883     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-17     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier B.V. All rights reserved.
Affiliation:
Department of Neurology, Korea University College of Medicine, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Aged
Analysis of Variance
Diabetes Mellitus, Type 2 / pathology*,  physiopathology
Electric Stimulation / methods
Electromyography / methods
History, 16th Century
Humans
Male
Middle Aged
Muscle Contraction / physiology
Neural Conduction / physiology*
Neural Inhibition / physiology*
Peripheral Nerves / physiopathology*
Reaction Time / physiology
Skin / innervation*
Statistics as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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