| Utility of TL-201 SPECT in clarifying false-positive FDG-PET findings due to osteoradionecrosis in head and neck cancer. | |
| | |
MedLine Citation:
|
PMID: 20848403 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
BACKGROUND: This study aimed to determine whether Tl-201 single photon emission CT (SPECT) is potentially useful in differentiating false-positive fluorodeoxyglucose positron emission tomography (FDG-PET) findings caused by osteoradionecrosis (ORN) from recurrent head and neck cancer after radiotherapy. METHODS: Five patients were recruited. Dual-phase FDG-PET and dual-phase Tl-201 SPECT were performed for each patient. RESULTS: All 5 patients proved to have ORN without recurrent cancer. By visual interpretation, the results were 4 positive versus 1 negative for PET, and 4 negative versus 1 positive for Tl-201 SPECT. The Tl-201 SPECT clarified 3 of the 4 false-positive PETs to be ORN. Dual-phase semiquantitative studies showed decreased standardized uptake value (SUV) over time in 3 of the 4 false-positive PETs and decreased lesion/background ratio over time in the false-positive Tl-201 SPECT. CONCLUSION: The Tl-201 SPECT may help clarify suspected false-positive FDG uptake caused by ORN. Dual-phase FDG-PET and dual-phase Tl-201 SPECT may also have some value. |
| | |
Authors:
|
Chih-Hsiu Wang; Ji-An Liang; Hueisch-Jy Ding; Shih-Neng Yang; Kuo-Yang Yen; Shung-Shung Sun; Chia-Hung Kao |
Related Documents
:
|
11212103 - The development of a potential single photon emission computed tomography (spect) imagi... 8970513 - Pre- and post-therapy thallium-201 and technetium-99m-sestamibi spect in nasopharyngeal... 12784573 - Psammomatoid ossifying fibroma of the ethmoid. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Head & neck Volume: 32 ISSN: 1097-0347 ISO Abbreviation: Head Neck Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8902541 Medline TA: Head Neck Country: United States |
Other Details:
|
Languages: eng Pagination: 1648-54 Citation Subset: IM |
Affiliation:
|
Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diminishing diagnosis of follicular thyroid carcinoma.
Next Document: Ultrasound-guided mechanical fragmentation of sialoliths (sonoguide forceps).