Document Detail

The utility of parent report in the assessment of working memory among childhood brain tumor survivors.
MedLine Citation:
PMID:  23351399     Owner:  NLM     Status:  MEDLINE    
Childhood brain tumor survivors are at increased risk for neurocognitive impairments, including working memory (WM) problems. WM is typically assessed using performance measures. Little is known about the value of parent ratings for identifying WM difficulties, the relationship between rater and performance measures, or predictors of parent-reported WM problems in this population. Accordingly, the current study examined the utility of parent report in detecting WM difficulties among childhood brain tumor survivors treated with conformal radiation therapy (n = 50) relative to siblings (n = 40) and solid tumor survivors not receiving central nervous system-directed therapy (n = 40). Parents completed the Behavior Rating Inventory of Executive Function (BRIEF). Participants were administered WM measures (digit span, self-ordered search tasks). Findings revealed parents rated brain tumor survivors as having significantly more WM problems (p < .01) compared to controls. However, the BRIEF-WM scale demonstrated poor sensitivity and specificity for detecting performance-based problems. Significant, albeit modest, correlations were found between the BRIEF-WM scale and performance measures (r = -.24-.22; p < .05) for the combined group. Age at testing, socioeconomic status, and IQ were significant predictors of parent reported WM problems. Rater and performance measures offer complimentary yet different information in assessing WM, which reiterates the importance of using both within the context of clinical assessment.
Robyn A Howarth; Jason M Ashford; Thomas E Merchant; Robert J Ogg; Victor Santana; Shengjie Wu; Xiaoping Xiong; Heather M Conklin
Related Documents :
16988769 - Preproenkephalin hypermethylation in the pure pancreatic juice compared with p53 mutati...
18346269 - Hypermethylated mal gene - a silent marker of early colon tumorigenesis.
2206779 - Effect of lactose derivatives on metastatic potential of b16 melanoma cells.
1777359 - Abnormal patterns of dna methylation in human neoplasia: potential consequences for tum...
16537559 - Plakoglobin is differentially expressed in alveolar and embryonal rhabdomyosarcoma and ...
8988039 - Reversal of loss of imprinting in tumor cells by 5-aza-2'-deoxycytidine.
2830009 - Papillary and cystic tumor of the pancreas. two cases indistinguishable from islet cell...
6456999 - Lymphoproliferative responses to autologous tumor extracts as prognostic indicators in ...
18278239 - Vestibular schwannoma: spontaneous tumor involution.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2013-01-28
Journal Detail:
Title:  Journal of the International Neuropsychological Society : JINS     Volume:  19     ISSN:  1469-7661     ISO Abbreviation:  J Int Neuropsychol Soc     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-17     Completed Date:  2013-12-10     Revised Date:  2014-04-02    
Medline Journal Info:
Nlm Unique ID:  9503760     Medline TA:  J Int Neuropsychol Soc     Country:  England    
Other Details:
Languages:  eng     Pagination:  380-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analysis of Variance
Brain Neoplasms / complications*
Chi-Square Distribution
Memory Disorders / diagnosis*,  etiology*
Memory, Short-Term / physiology*
Neuropsychological Tests
Parents / psychology*
Personality Inventory
Survivors / psychology*
Grant Support
P30 CA021765/CA/NCI NIH HHS; P30 CA21765/CA/NCI NIH HHS; R21 CA131616/CA/NCI NIH HHS; R21 CA131616/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Preparation and evaluation of inhalable itraconazole chitosan based polymeric micelles.
Next Document:  Founder mutations and genotype-phenotype correlations in Meckel-Gruber syndrome and associated cilio...