Document Detail

Utility of High Resolution Electroanatomic Mapping of the Left Ventricle Using a Multispline Basket Catheter in a Swine Model of Chronic Myocardial Infarction.
MedLine Citation:
PMID:  25173890     Owner:  NLM     Status:  Publisher    
BACKGROUND: Standard electroanatomic mapping systems use a single catheter to perform left ventricular (LV) substrate mapping. A new mapping system uses a 64-electrode mini-basket catheter to perform rapid automated acquisition of chamber geometry, voltage and activation.
OBJECTIVE: The aim of this study was to compare the accuracy of the basket catheter to standard catheter mapping in a swine model of chronic myocardial infarction.
METHODS: Ten swine underwent left anterior descending coronary artery occlusion to create an anteroseptal myocardial infarction. Animals underwent delayed-enhancement MRI and then detailed LV voltage mapping using both the basket and linear catheter. Map characteristics and scar area were compared between the basket, linear, and MRI. Induced ventricular tachycardia (VT) was mapped with the basket catheter.
RESULTS: There were more points acquired using the basket catheter compared to the standard catheter (8,762±3,164 vs. 1,712±551; p<0.001). The 5(th) percentile of normal bipolar voltage distribution using the basket catheter was 1.54mV. Using bipolar voltage cutoff of 1.5mV, the total infarct areas measured by basket, linear and MRI were similar (17.8 vs. 20.9 vs. 17.5cm(2); p=0.69); however the correlation between MRI and catheter scar area measurement was best for the basket (r=0.76 basket vs. 0.71 linear). In 3 animals, sustained poorly tolerated VT was initiated and the circuit mapped successfully with basket catheter in <5 minutes.
CONCLUSION: Rapid substrate and activation mapping using a 64-electrode mini-basket catheter allows detailed voltage and activation mapping in post-infarction cardiomyopathy. This system may be useful for substrate and VT mapping in human post-infarction cardiomyopathy.
Yasuaki Tanaka; Martin Genet; Lik Chuan Lee; Alastair J Martin; Richard Sievers; Edward P Gerstenfeld
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-27
Journal Detail:
Title:  Heart rhythm : the official journal of the Heart Rhythm Society     Volume:  -     ISSN:  1556-3871     ISO Abbreviation:  Heart Rhythm     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101200317     Medline TA:  Heart Rhythm     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Inc.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Anti-Inflammatory and Membrane-Stabilizing Properties of Two Semisynthetic Derivatives of Oleanolic ...
Next Document:  Connective tissues reflect different mechanisms of strabismus over the life span.