Document Detail


Uterine rupture during second-trimester abortion associated with misoprostol.
MedLine Citation:
PMID:  11704229     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Misoprostol use is contraindicated in women at term with a history of a uterine scar. There are limited data regarding the use of this drug in the midtrimester. CASE: A 23-year-old woman with two prior cesareans presented at 23 weeks' gestation for pregnancy termination by dilation and evacuation. She had laminariae placed the day before and was instructed to take 400 microg of misoprostol intravaginally at midnight, then 400 microg buccally at 6:00 AM the day of the procedure. During the evacuation, uterine rupture was diagnosed. She underwent emergency laparotomy, and the uterus was repaired. CONCLUSION: Uterine rupture can occur when misoprostol is used in the second trimester in a woman with a uterine scar.
Authors:
L Berghahn; D Christensen; S Droste
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  98     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-11-12     Completed Date:  2001-12-05     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  976-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin 53792, USA. ljberghahn@hosp.wisc.edu
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MeSH Terms
Descriptor/Qualifier:
Abortifacient Agents, Nonsteroidal / adverse effects*,  contraindications
Adult
Cesarean Section
Female
Humans
Misoprostol / adverse effects*,  contraindications
Pregnancy
Pregnancy Trimester, Second
Uterine Rupture / etiology*
Chemical
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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