Document Detail


Uterine radiation dose from open sources: the potential for underestimation.
MedLine Citation:
PMID:  2083549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The evaluation of the risk of radiation damage to the unborn child as the result of the administration of radionuclides remains a subject for discussion (Mountford 1989). Lack of information concerning the biodistribution of radiopharmaceuticals in the early stages of pregnancy, before organogenesis has occurred, has greatly restricted the objective assessment of fetal doses. Recent observations on the biodistribution of a therapeutic dose of sodium iodide 131 in a patient with an unsuspected early pregnancy lead us to suspect that current dose estimates with respect to uterine exposure (ARSAC 1988) may seriously underestimate the actual exposure of the developing fetus.
Authors:
P H Cox; J G Klijn; M Pillay; M Bontebal; D H Schönfeld
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  17     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  1990  
Date Detail:
Created Date:  1991-05-14     Completed Date:  1991-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  94-5     Citation Subset:  IM    
Affiliation:
Dr. Daniel Den Hoed Cancer Centre, Rotterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Radiation-Induced / prevention & control*
Female
Humans
Iodine Radioisotopes / therapeutic use*
Pregnancy
Pregnancy Trimester, First
Radiation Dosage
Risk Factors
Sodium Iodide / therapeutic use*
Thyroid Neoplasms / radiotherapy*
Uterus / radiation effects*
Chemical
Reg. No./Substance:
0/Iodine Radioisotopes; 7681-82-5/Sodium Iodide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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