| Uterine and placental angiogenesis in the Australian skinks, Ctenotus taeniolatus, and Saiphos equalis. | |
| | |
MedLine Citation:
|
PMID: 20432373 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The evolution of viviparity requires modifications to multiple integrated physiological features to support embryonic development during pregnancy. Embryonic growth during pregnancy is dependent upon the capacity of the uterine vascular system to satisfy increasing embryonic oxygen demand throughout gestation. We tested the hypothesis that total surface area of uterine blood vessels increases in concert with embryonic growth, and hence its oxygen demand, during gestation. We used immunofluorescence and laser-scanning confocal microscopy to quantify uterine microvascular density and morphology during gestation in the oviparous skink Ctenotus taeniolatus and in Saiphos equalis, a skink species with prolonged egg retention. For C. taeniolatus, vessel density (Nv) and vessel length-density (Lv) in the embryonic hemisphere of the uterus is 23% and 17% less, respectively, than that of S. equalis and vascular surface-area does not differ as a function of embryo stage. For S. equalis, overall Nv, Lv, and vessel diameter (Dv), does not change during the first half of gestation but increases by 36% (Nv), 44% (Lv), and 60% (Dv) by near-term embryo stages late in gestation. The chorioallantoic membrane of S. equalis increases in absolute size but vascular density does not differ as a function of embryo stage. The marked increase in uterine vascular density during late gestation coincides with the phase of rapid growth in embryo mass and concomitant increase in metabolic rate. Expansion of the uterine vascular bed in concert with embryo size and metabolism is likely to be an important transitional step in the evolution of viviparity. |
| | |
Authors:
|
Scott L Parker; Frank Manconi; Christopher R Murphy; Michael B Thompson |
Related Documents
:
|
11948673 - Variation in eggshell characteristics and in intrauterine egg retention between two ovi... 9623493 - Embryo development and placentome formation during early pregnancy in red deer. 17701803 - Efficacy of a single misoprostol regimen in the first and second trimester termination ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Anatomical record (Hoboken, N.J. : 2007) Volume: 293 ISSN: 1932-8494 ISO Abbreviation: Anat Rec (Hoboken) Publication Date: 2010 May |
Date Detail:
|
Created Date: 2010-04-30 Completed Date: 2010-08-10 Revised Date: 2010-09-09 |
Medline Journal Info:
|
Nlm Unique ID: 101292775 Medline TA: Anat Rec (Hoboken) Country: United States |
Other Details:
|
Languages: eng Pagination: 829-38 Citation Subset: IM |
Affiliation:
|
Integrative Physiology Research Group, School of Biological Sciences, The University of Sydney, Sydney, New South Wales, Australia. sparker@coastal.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Basal Metabolism / physiology Chorioallantoic Membrane / blood supply, embryology Embryo, Nonmammalian / blood supply, embryology Embryonic Development / physiology* Female Fluorescent Antibody Technique Lizards / anatomy & histology*, physiology Microscopy, Confocal Neovascularization, Physiologic / physiology* Placenta / blood supply*, physiology Regional Blood Flow / physiology Uterine Artery / anatomy & histology, physiology Uterus / blood supply*, physiology Viviparity, Nonmammalian / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Alendronate affects cartilage resorption by regulating vascular endothelial growth factor expression...
Next Document: Effect of the photoperiod and administration of melatonin on the pars tuberalis of viscacha (Lagosto...