| Uterine myomas during pregnancy: a longitudinal sonographic study. | |
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MedLine Citation:
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PMID: 20922776 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate volumetric changes of uterine myomas (fibroids) during pregnancy. METHODS: This was an observational, longitudinal and prospective study of 38 consecutive Caucasian women with singleton pregnancies and a total of 42 uterine myomas, enrolled from a cohort of 1492 women who took part in our first-trimester Down syndrome screening program. Myoma volume was evaluated by ultrasound at 11-14, 20-22 and 32-34 weeks of gestation. RESULTS: Mean myoma volume increased significantly throughout pregnancy. Taking a volumetric change of > 10% between gestational periods to be an increase in size, 71.4% of uterine myomas increased in size between the first and second gestational periods, while this percentage was slightly lower (66.6%) between the second and third periods. Logistic regression analysis revealed that greater maternal age was correlated with a reduction/no change in overall myoma size and multiparity was correlated with a decrease/no change between the first and second trimesters, while a higher prepregnancy maternal body mass index (BMI) was correlated with a volumetric increase between the first and second trimesters and a decrease/no change between the second and third trimesters. CONCLUSIONS: Fibroids enlarge during pregnancy regardless of their initial size or local factors, and maternal age, prepregnancy BMI and parity are apparently correlated with these changes. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd. |
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Authors:
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A De Vivo; A Mancuso; A Giacobbe; L Maggio Savasta; R De Dominici; N Dugo; C Dugo; A Vaiarelli |
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Publication Detail:
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Type: Journal Article Date: 2011-02-10 |
Journal Detail:
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Title: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology Volume: 37 ISSN: 1469-0705 ISO Abbreviation: Ultrasound Obstet Gynecol Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9108340 Medline TA: Ultrasound Obstet Gynecol Country: England |
Other Details:
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Languages: eng Pagination: 361-5 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd. |
Affiliation:
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Department of Gynecological, Obstetrical Sciences and Reproductive Medicine, University Hospital, Messina, Italy. antonio.devivo@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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