Document Detail

Uterine leiomyoma with massive lymphoid infiltration: case report and review of the literature.
MedLine Citation:
PMID:  15086839     Owner:  NLM     Status:  MEDLINE    
Uterine leiomyoma with massive lymphoid infiltration is a rare and unusual pathological finding. Only 13 cases have been reported in English literature. A case of uterine leiomyoma showing massive lymphoid infiltration in a 45-year-old woman is described. The tumor was relatively soft compared with usual leiomyomas. Microscopically, the tumor showed the typical features of leiomyoma with moderate to severe lymphocytic infiltrate consisting of mature lymphocytes, a few plasma cells and occasional histiocytes. This cellular infiltration was confined to the leiomyoma. Immunohistochemically, the diffusely infiltrated lymphoid cells were stained by antibodies to CD45RO, CD3 and CD8. Germinal centers were stained by antibodies to CD20 and CD79a. Some CD68+ histiocytes were seen. Lymphoid infiltration within the leiomyoma is a peculiar histological morphology, although the cause is not clear. The recognition of its distinct histological features is important to avoid possible confusion with differential diagnoses including malignant lymphoma, inflammatory pseudotumor and pyomyoma.
Seung Sam Paik; Young-Ha Oh; Ki Seok Jang; Hong Xiu Han; Sam Hyun Cho
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology international     Volume:  54     ISSN:  1320-5463     ISO Abbreviation:  Pathol. Int.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-04-16     Completed Date:  2004-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9431380     Medline TA:  Pathol Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  343-8     Citation Subset:  IM    
Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
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MeSH Terms
Antigens, CD / metabolism
Diagnosis, Differential
Granuloma, Plasma Cell
In Situ Nick-End Labeling
Leiomyoma / metabolism,  pathology*
Lymphocytes / pathology*
Lymphoma / pathology
Middle Aged
Neutrophil Infiltration*
Uterine Neoplasms / metabolism,  pathology*
Reg. No./Substance:
0/Antigens, CD

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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