| Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids (EMMY trial): peri- and postprocedural results from a randomized controlled trial. | |
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MedLine Citation:
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PMID: 16260201 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: This was a randomized controlled trial to evaluate the safety of uterine artery embolization (UAE) compared with hysterectomy. STUDY DESIGN: Twenty-eight Dutch hospitals recruited 177 patients with symptomatic uterine fibroids and menorrhagia who were eligible for hysterectomy. Patients were randomized to UAE (n = 88) or hysterectomy (n = 89). In this paper we evaluate the peri- and postprocedural complications, length of hospital stay, unscheduled visits, and readmission rates up to 6 weeks' post-intervention. Analysis was by intention to treat. RESULTS: Bilateral UAE failure occurred in 4 patients (4.9%). Major complications occurred in 4.9% (UAE) and 2.7% (hysterectomy) of cases (P = .68). The minor complication rate from discharge until 6 weeks after was significantly higher in the UAE group than in the hysterectomy group (58.0% vs 40.0%; RR 1.45 [1.04-2.02]; P = .024). UAE patients were more often readmitted (11.1% vs 0%; P = .003). Total length of hospital stay was significantly shorter in UAE patients (mean [SD]: 2.5 [2.7] vs 5.1 [1.3], P < .001). CONCLUSION: UAE is a procedure similar to hysterectomy with a low major complication rate and with a reduced length of hospital stay. Higher readmission rates after UAE stress the need for careful postprocedural follow-up. |
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Authors:
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Wouter J K Hehenkamp; Nicole A Volkers; Peter F J Donderwinkel; Sjoerd de Blok; Erwin Birnie; Willem M Ankum; Jim A Reekers |
Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 193 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-11-01 Completed Date: 2006-01-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1618-29 Citation Subset: AIM; IM |
Affiliation:
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Department of Gynecology, Academic Medical Center, Amsterdam, The Netherlands. w.j.k.hehenkamp@amc.uva.nl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arteries Embolization, Therapeutic* / adverse effects, methods Female Follow-Up Studies Hospitalization Humans Hysterectomy* / adverse effects, methods Leiomyoma / surgery* Middle Aged Postoperative Complications / epidemiology Uterine Neoplasms / surgery* Uterus / blood supply* |
| Comments/Corrections | |
Comment In:
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Am J Obstet Gynecol. 2006 Oct;195(4):1190; author reply 1191
[PMID:
17000261
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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