| Uterine artery embolization compared with methotrexate for the management of pregnancy implanted within a cesarean scar. | |
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MedLine Citation:
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PMID: 19527897 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of the study was to compare the efficacy and safety of uterine artery embolization (UAE) vs systemic methotrexate (MTX) for pregnancy within a cesarean scar. STUDY DESIGN: Seventy-two women with pregnancy within cesarean scar were randomly allocated to a UAE group (37 cases) or an MTX group (35 cases), which all was followed by suction curettage. The primary outpoints include bleeding loss, serum beta-human chorionic gonadotropin level, and side effects. RESULTS: The bleeding volumes were 36.93 +/- 6.01 mL in the UAE group and 415.63 +/- 68.37 mL in the MTX group (P < .001). The hospitalization time was 11.73 +/- 0.80 days in the UAE group and 39.63 +/- 4.57 days in the MTX group (P < .001). There was no severe side effect in both groups. CONCLUSION: For pregnancy within a cesarean scar, UAE followed by suction curettage appears to have more advantage and may be a priority option. |
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Authors:
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YaLing Zhuang; LiLi Huang |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial Date: 2009-06-13 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 201 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-08-03 Completed Date: 2009-08-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 152.e1-3 Citation Subset: AIM; IM |
Affiliation:
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Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310006, People's Republic of China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents, Nonsteroidal
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therapeutic use* Abortion, Induced / methods Adult Cicatrix Combined Modality Therapy Embryo Implantation Female Humans Methotrexate / therapeutic use* Pregnancy Pregnancy, Ectopic / drug therapy*, surgery*, ultrasonography Prospective Studies Uterine Artery Embolization* Uterine Hemorrhage / prevention & control Uterus / blood supply, pathology |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents, Nonsteroidal; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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