Document Detail


Uterine artery embolization compared with methotrexate for the management of pregnancy implanted within a cesarean scar.
MedLine Citation:
PMID:  19527897     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The objective of the study was to compare the efficacy and safety of uterine artery embolization (UAE) vs systemic methotrexate (MTX) for pregnancy within a cesarean scar. STUDY DESIGN: Seventy-two women with pregnancy within cesarean scar were randomly allocated to a UAE group (37 cases) or an MTX group (35 cases), which all was followed by suction curettage. The primary outpoints include bleeding loss, serum beta-human chorionic gonadotropin level, and side effects. RESULTS: The bleeding volumes were 36.93 +/- 6.01 mL in the UAE group and 415.63 +/- 68.37 mL in the MTX group (P < .001). The hospitalization time was 11.73 +/- 0.80 days in the UAE group and 39.63 +/- 4.57 days in the MTX group (P < .001). There was no severe side effect in both groups. CONCLUSION: For pregnancy within a cesarean scar, UAE followed by suction curettage appears to have more advantage and may be a priority option.
Authors:
YaLing Zhuang; LiLi Huang
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-06-13
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  201     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-03     Completed Date:  2009-08-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  152.e1-3     Citation Subset:  AIM; IM    
Affiliation:
Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310006, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Abortifacient Agents, Nonsteroidal / therapeutic use*
Abortion, Induced / methods
Adult
Cicatrix
Combined Modality Therapy
Embryo Implantation
Female
Humans
Methotrexate / therapeutic use*
Pregnancy
Pregnancy, Ectopic / drug therapy*,  surgery*,  ultrasonography
Prospective Studies
Uterine Artery Embolization*
Uterine Hemorrhage / prevention & control
Uterus / blood supply,  pathology
Chemical
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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