| Uterine anomaly and recurrent pregnancy loss. | |
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MedLine Citation:
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PMID: 22161464 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Women with recurrent pregnancy loss have a 3.2 to 6.9% likelihood of having a major uterine anomaly and a 1.0 to 16.9% chance of having an arcuate uterus. Bicornuate and septate uterine have a negative impact on reproductive outcomes and are associated with subsequent euploid miscarriage. The impact of an arcuate uterus on pregnancy outcome remains unclear. There are no definitive criteria to distinguish among the arcuate, septate, and bicornuate uteri. The American Fertility Society classification of Müllerian anomalies is the most common standardized classification of uterine anomalies. According to estimates, 65 to 85% of patients with bicornuate or septate uteri have a successful pregnancy outcome after metroplasty. However, 59.5% of the patients with such anomalies have a successful subsequent pregnancy without surgery, with a cumulative live birthrate of 78.0%. There is no case-control study to compare live birthrates in women who had surgery compared with those who did not. Strict criteria to distinguish between the bicornuate and septate uterus should be established. Further study is needed to confirm the benefits of metroplasty. |
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Authors:
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Mayumi Sugiura-Ogasawara; Yasuhiko Ozaki; Kinue Katano; Nobuhiro Suzumori; Eita Mizutani |
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Publication Detail:
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Type: Journal Article Date: 2011-12-08 |
Journal Detail:
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Title: Seminars in reproductive medicine Volume: 29 ISSN: 1526-4564 ISO Abbreviation: Semin. Reprod. Med. Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100909394 Medline TA: Semin Reprod Med Country: United States |
Other Details:
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Languages: eng Pagination: 514-21 Citation Subset: IM |
Copyright Information:
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© Thieme Medical Publishers. |
Affiliation:
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Department of Obstetrics and Gynecology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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