Document Detail


Using a gel/plastic surrogate to study the biomechanical response of the head under air shock loading: a combined experimental and numerical investigation.
MedLine Citation:
PMID:  21590345     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A combined experimental and numerical study was conducted to determine a method to elucidate the biomechanical response of a head surrogate physical model under air shock loading. In the physical experiments, a gel-filled egg-shaped skull/brain surrogate was exposed to blast overpressure in a shock tube environment, and static pressures within the shock tube and the surrogate were recorded throughout the event. A numerical model of the shock tube was developed using the Eulerian approach and validated against experimental data. An arbitrary Lagrangian-Eulerian (ALE) fluid-structure coupling algorithm was then utilized to simulate the interaction of the shock wave and the head surrogate. After model validation, a comprehensive series of parametric studies was carried out on the egg-shaped surrogate FE model to assess the effect of several key factors, such as the elastic modulus of the shell, bulk modulus of the core, head orientation, and internal sensor location, on pressure and strain responses. Results indicate that increasing the elastic modulus of the shell within the range simulated in this study led to considerable rise of the overpressures. Varying the bulk modulus of the core from 0.5 to 2.0 GPa, the overpressure had an increase of 7.2%. The curvature of the surface facing the shock wave significantly affected both the peak positive and negative pressures. Simulations of the head surrogate with the blunt end facing the advancing shock front had a higher pressure compared to the simulations with the pointed end facing the shock front. The influence of an opening (possibly mimicking anatomical apertures) on the peak pressures was evaluated using a surrogate head with a hole on the shell of the blunt end. It was revealed that the presence of the opening had little influence on the positive pressures but could affect the negative pressure evidently.
Authors:
Feng Zhu; Christina Wagner; Alessandra Dal Cengio Leonardi; Xin Jin; Pamela Vandevord; Clifford Chou; King H Yang; Albert I King
Related Documents :
16892645 - Triamcinolone-induced intraocular pressure elevation: intravitreal injection for macula...
15990605 - Timolol/dorzolamide combination therapy as initial treatment for intraocular pressure o...
1420055 - Ocular circulatory changes following scleral buckling procedures.
20516145 - Twenty-four-hour ocular perfusion pressure in primary open-angle glaucoma.
21189915 - A comparative study of nebivolol and (s) atenolol on blood pressure and heart rate on e...
8459965 - Cigarette smoking during pregnancy: acute effects on uterine flow velocity waveforms.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-18
Journal Detail:
Title:  Biomechanics and modeling in mechanobiology     Volume:  -     ISSN:  1617-7940     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101135325     Medline TA:  Biomech Model Mechanobiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Bioengineering Center, Wayne State University, Detroit, MI, 48201, USA, fengzhume@gmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Role of endogenous hydrogen sulfide on renal damage induced by adriamycin injection.
Next Document:  Dietary Protein Intake and Bariatric Surgery Patients: A Review.