Document Detail


Using middle cerebral artery peak systolic velocity to time in utero transfusions in fetomaternal hemorrhage.
MedLine Citation:
PMID:  20410780     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Fetomaternal hemorrhage is a rare cause of fetal anemia and hydrops fetalis. Early and severe fetomaternal hemorrhage may benefit from in utero transfusion(s); however, hemorrhage rate is unpredictable, and reliable criteria are needed to identify recurrent anemia. CASE: Fetal hydrops due to massive fetomaternal hemorrhage was diagnosed at 29 weeks. After the first in utero transfusion, daily monitoring of middle cerebral artery peak systolic velocity suggested recurrent fetal anemia, requiring two additional in utero transfusions at 1-week intervals. One day after the third in utero transfusion, a sudden increase in fetomaternal hemorrhage rate was suspected on a rapid elevation of middle cerebral artery peak systolic velocity, leading to immediate delivery at 32 weeks. CONCLUSION: Middle cerebral artery peak systolic velocity is a relevant, noninvasive tool for the timing of repeated in utero transfusions and of fetal delivery in case of chronic fetomaternal hemorrhage.
Authors:
St?phanie Friszer; Anne Cortey; Fabrice Pierre; Bruno Carbonne
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  115     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-22     Completed Date:  2010-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1036-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology and the Centre National de R?f?rence en H?mobiologie P?rinatale, H?pital Saint-Antoine, Assistance Publique-H?pitaux de Paris, Universit? Pierre et Marie Curie, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity
Blood Transfusion*
Chronic Disease
Female
Fetomaternal Transfusion / physiopathology*,  therapy*
Humans
Hydrops Fetalis / etiology,  ultrasonography
Middle Cerebral Artery / physiopathology*
Monitoring, Physiologic
Pregnancy
Retreatment
Ultrasonography, Doppler
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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