Document Detail

MedLine Citation:
PMID:  12685429     Owner:  NLM     Status:  MEDLINE    
While considerable advances have been made in the understanding of the tissue-destructive mechanisms involved in etiology of periodontitis, the adoption and application of this knowledge has not been generally incorporated into the daily management of patients with chronic periodontitis. A number of adjunctive pharmacotherapeutic agents have been investigated in clinical trials and several agents are used in everyday practice as adjuncts to mechanical nonsurgical periodontal therapy. The only systemic, host modulatory agent approved for the adjunctive use with nonsurgical periodontal procedures, however, is Periostat (20mg doxycycline hyclate, twice daily). In order to further understand the impact of adjunctive host modulatory therapy on patient management and its role in clinical practice, Montage Media interviewed dental professionals across the US. Each of the participants has direct experience with the use of Periostat in their clinical practice. The expectation is that, with the "real life" clinical experience reported by clinicians "in their own words" coupled with the extensive literature describing the results of controlled clinical trials of Periostat, it will be possible to hasten the adoption of evidence-based science into clinical practice.
Steven Chichetti; Herbert Bader; Scott Smith; Nancy Barnett; Richard Barecki; Diane Testa; Jennifer Giannini; Dori Bass; Isabel Vines; Philip DiSalvo
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Publication Detail:
Type:  Interview    
Journal Detail:
Title:  Practical procedures & aesthetic dentistry : PPAD     Volume:  14     ISSN:  1534-6846     ISO Abbreviation:  Pract Proced Aesthet Dent     Publication Date:    2002 Nov-Dec
Date Detail:
Created Date:  2003-04-09     Completed Date:  2003-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101089932     Medline TA:  Pract Proced Aesthet Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  suppl 12-5     Citation Subset:  D    
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MeSH Terms
Dentist-Patient Relations
Doxycycline / analogs & derivatives*,  therapeutic use*
Immunologic Factors / therapeutic use*
Patient Compliance
Patient Education as Topic
Periodontitis / drug therapy*
Reg. No./Substance:
0/Immunologic Factors; 24390-14-5/doxycycline hyclate; 564-25-0/Doxycycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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