Document Detail

Using a generic measure of quality of life in patients with obstructive sleep apnea.
MedLine Citation:
PMID:  20967570     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: To evaluate the utility of a Multicultural Quality of Life Index (MQLI) in patients with Obstructive Sleep Apnea-Hypopnea (OSAH).
METHODS: Physical examination, MQLI and the Epworth Sleepiness Scale (ESS) were applied to participants. In addition, a polysomnography or a respiratory polygraphy was carried out.
RESULTS: A total of 221 patients participated, 186 (84%) males, mean age 48.8 ± 11.8 years. The MQLI scores 7were .73 ± 1.45 and the ESS 9.9 ± 5.2. A total of 188 (85%) patients had OSAH: 40 (21%) mild, 43 (23%) moderate, and 105 (56%) severe. The average time to answer the MQLI was 3.5 min. Cronbach's alpha index was 0.930. MQLI score in patients with and without OSAH was 7.73 versus 7.75 (p = 0.949); and by severity: non-OSAH 7.75, mild 8.04, moderate 8.14, and severe 7.44 (p = 0.023). There was a slight correlation between MQLI score and Apnea-Hypopnea Index in total population, but it disappeared when we analyzed by severity. MQLI and ESS correlation was R = -0.3256 (p < 0.0001).
CONCLUSIONS: The MQLI has limitations in identifying quality of life (QOL) alterations and a poor correlation with severity in OSAH patients. The MQLI quantifies QOL in a general way. We recommend supplementing the QOL evaluation with disease-specific instruments.
Jorge Rey de Castro; Edmundo Rosales-Mayor; Jenny Ferreyra-Pereyra
Publication Detail:
Type:  Journal Article     Date:  2010-10-22
Journal Detail:
Title:  Sleep & breathing = Schlaf & Atmung     Volume:  15     ISSN:  1522-1709     ISO Abbreviation:  Sleep Breath     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9804161     Medline TA:  Sleep Breath     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  729-35     Citation Subset:  IM    
Centro de Trastornos Respiratorios del Sueño (CENTRES), Clínica Anglo Americana, Av. Alfredo Salazar 314, San Isidro, Lima, 27, Peru,
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