Document Detail

Using evidence in pain practice: Part I: Assessing quality of systematic reviews and clinical practice guidelines.
MedLine Citation:
PMID:  18346062     Owner:  NLM     Status:  MEDLINE    
The best evidence should inform all clinical decisions, but physicians cannot realistically keep up with all of the literature. Two types of preprocessed evidence that can help busy clinicians incorporate evidence into everyday medical decision-making are systematic reviews and clinical practice guidelines. However, conclusions of systematic reviews and recommendations of evidence-based clinical practice guidelines should not be accepted at face value. Like primary studies, they must adhere to rigorous standards in order to reduce error and bias. In fact, low-quality systematic reviews and guidelines can be very misleading. This article discusses what factors distinguish a high-quality systematic review. It also examines the difference between systematic reviews and clinical practice guidelines, and what factors distinguish a high-quality guideline. A separate article discusses how to interpret and apply systematic reviews and clinical practice guidelines, particularly when evidence is weak or inconclusive, or when different systematic reviews or guidelines are discordant.
Roger Chou
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pain medicine (Malden, Mass.)     Volume:  9     ISSN:  1526-4637     ISO Abbreviation:  Pain Med     Publication Date:    2008 Jul-Aug
Date Detail:
Created Date:  2008-09-05     Completed Date:  2008-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100894201     Medline TA:  Pain Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  518-30     Citation Subset:  IM    
Oregon Evidence-Based Practice Center, Department of Medicine, Oregon Health and Science University, Portland, Oregon, USA.
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MeSH Terms
Clinical Trials as Topic
Evidence-Based Medicine / standards*
Pain / physiopathology,  therapy*
Peer Review, Research
Practice Guidelines as Topic / standards*
Quality Control
Random Allocation
Review Literature as Topic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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