Document Detail


Using case-control studies to assess the prevention of inflicted traumatic brain injury.
MedLine Citation:
PMID:  18374267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Because the incidence of inflicted traumatic brain injury (inflicted TBI) is low, even in populations at increased risk, very large samples are necessary to have adequate statistical power to conduct a randomized clinical trial of the effectiveness of a potential intervention to prevent inflicted TBI. This requirement for large samples, in addition to the logistic demands of prospective clinical trials, makes it prohibitively expensive to conduct such studies. Case-control studies provide a statistically efficient and logistically and economically feasible alternative approach to evaluating such interventions. However, because these are observational studies, they are susceptible to bias. Approaches are presented to conducting and analyzing case-control studies to evaluate interventions to prevent inflicted TBI while assessing and minimizing possible bias.
Authors:
Eugene D Shapiro
Related Documents :
12662187 - Course of migraine during pregnancy and postpartum: a prospective study.
3752917 - Ethnic difference in duration of pregnancy.
16959307 - Smoking in early gestation or through pregnancy: a decision crucial to pregnancy outcome.
22935277 - Scaling and root planing performed on pregnant women with mild to moderate periodontal ...
463647 - Induction of tolerance to dncb-contact sensitivity in guinea pig fetuses.
16830077 - The impact of fetal echocardiography on the prevalence of liveborn congenital heart dis...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  American journal of preventive medicine     Volume:  34     ISSN:  0749-3797     ISO Abbreviation:  Am J Prev Med     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-31     Completed Date:  2008-07-02     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  8704773     Medline TA:  Am J Prev Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  S153-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Bias (Epidemiology)
Brain Injuries / prevention & control*
Case-Control Studies*
Child, Preschool
Humans
Program Evaluation* / methods
Grant Support
ID/Acronym/Agency:
K24 RR022477/RR/NCRR NIH HHS; K24 RR022477-07/RR/NCRR NIH HHS; RR022477/RR/NCRR NIH HHS; UL1 RR024139/RR/NCRR NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evaluating the effect of an injury prevention intervention in a population.
Next Document:  Using hospital discharge data to track inflicted traumatic brain injury.