Document Detail

Usefulness of vacuum-assisted cardiopulmonary bypass circuit for pediatric open-heart surgery in reducing homologous blood transfusion.
MedLine Citation:
PMID:  11463537     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Open-heart surgery without homologous blood transfusion is still difficult in children because priming volume in cardiopulmonary bypass circuit results in extreme hemodilution. Vacuum-assisted cardiopulmonary bypass circuit has the benefit of improving venous return and results in lowering priming volume. We introduced vacuum-assisted cardiopulmonary bypass circuit in order to reduce priming volume for pediatric patients in March 1995. A retrospective study was made on the efficacy of vacuum-assisted circuit for pediatric open-heart surgery in reducing homologous blood transfusion. METHODS: Patients weighing from 5 to 20 kg who underwent surgery between January 1991 and June 1996 were divided into two groups, group A comprised 128 patients before introduction of this circuit and group B comprised 49 patients after introduction, and their clinical course was compared. Vacuum-assisted circuit was used in 27 patients of group B. RESULTS: The percentage of transfusion-free operations was significantly higher in group B than in group A (33.6% in group A vs. 53.1% in group B, P = 0.014), and particularly this percentage in patients weighing less than 10 kg significantly increased (0% in group A vs. 42.9% in group B, P < 0.01). The amount of homologous blood transfusion was significantly lower in group B than in group A (374 +/- 362 ml in group A and 212 +/- 287 ml in group B, P < 0.01). The rate of complications and the duration of respiratory support did not differ between the two groups. The duration of hospital stay was lower in group B than in group A. CONCLUSIONS: The findings of this study indicate that vacuum-assisted circuit is useful for pediatric open-heart surgery in reducing homologous blood transfusion.
K Nakanishi; T Shichijo; Y Shinkawa; S Takeuchi; M Nakai; G Kato; O Oba
Related Documents :
7730247 - Centrifugal and roller pumps--are there differences in coagulation and fibrinolysis dur...
1672247 - Effect of desmopressin acetate on hemorrhage without identifiable cause in coronary byp...
11973167 - Perioperative melatonin secretion in patients undergoing coronary artery bypass grafting.
12645727 - Complement activation and cytokine and chemokines release during mediastinitis.
15644407 - Nutritional and cognitive relationships and long-term mortality in patients with variou...
20711527 - The rate of prescribing gastrointestinal prophylaxis with either a proton pump inhibito...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  20     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-20     Completed Date:  2001-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  233-8     Citation Subset:  IM    
Department of Cardiovascular Surgery, Hiroshima City Hospital, Hiroshima, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Transfusion
Cardiac Surgical Procedures*
Cardiopulmonary Bypass / methods*
Child, Preschool
Heart Defects, Congenital / surgery*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Double inlet right ventricle versus other types of double or common inlet ventricle: its clinical ch...
Next Document:  Is there still a place for open surgical valvotomy in the management of aortic stenosis in children?...