| Usefulness of polyethylene glycol solution with dimethylpolysiloxanes for bowel preparation before capsule endoscopy. | |
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MedLine Citation:
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PMID: 19793169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND AIM: Capsule endoscopy (CE) is widely used for diagnosing small intestinal diseases. In some cases, however, observation of target sites is very poor during CE because of residues etc. Herein we report the usefulness of a preparation comprised of polyethylene glycol solution (PEG) for CE. METHODS: This was a prospective, randomized, and single-blind study. Forty subjects, fasted for 12 h before CE, were randomized into two groups: 20 subjects in Group A were fasted only, whereas 20 in Group B received 1 liter (L) PEG with 200 mg dimethylpolysiloxane 3 h before CE. For evaluation, the observation period of the small intestine was divided into first and second halves. Subsequently, four investigators, blinded as to which group received the preparation, assessed the condition of the intestine using four rating scales in terms of 'residue' and 'intraluminal gas bubbles'. The effects of the preparation were statistically compared. RESULTS: CE images were better in Group B than in Group A with respect to 'intraluminal gas bubbles' (P = 0.0038) in the first half of the observation period, as well as residue (P = 0.0087) and intraluminal gas bubbles (P = 0.0011) in the second half. CONCLUSION: Bowel preparation using 1 L PEG with dimethylpolysiloxane 3 h before CE significantly reduced residue and intraluminal gas bubbles, and was considered to be a useful method for CE. |
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Authors:
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Sadaharu Nouda; Eijiro Morita; Mitsuyuki Murano; Akira Imoto; Takanori Kuramoto; Takuya Inoue; Naoko Murano; Ken Toshina; Eiji Umegaki; Kazuhide Higuchi |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2009-09-27 |
Journal Detail:
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Title: Journal of gastroenterology and hepatology Volume: 25 ISSN: 1440-1746 ISO Abbreviation: J. Gastroenterol. Hepatol. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-02-08 Completed Date: 2010-05-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607909 Medline TA: J Gastroenterol Hepatol Country: Australia |
Other Details:
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Languages: eng Pagination: 70-4 Citation Subset: IM |
Affiliation:
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Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan. sadaharu.nouda.1110@hotmail.co.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Antifoaming Agents / therapeutic use* Capsule Endoscopy* Dimethylpolysiloxanes / therapeutic use* Fasting Female Gases Gastrointestinal Agents / therapeutic use* Humans Intestinal Diseases / pathology* Intestine, Small / pathology* Male Middle Aged Pharmaceutical Solutions Polyethylene Glycols / therapeutic use* Predictive Value of Tests Prospective Studies Single-Blind Method Time Factors Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antifoaming Agents; 0/Dimethylpolysiloxanes; 0/Gases; 0/Gastrointestinal Agents; 0/Pharmaceutical Solutions; 0/Polyethylene Glycols |
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