| Usefulness of a new proposed tissue Doppler imaging global function index in hypertrophic cardiomyopathy. | |
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MedLine Citation:
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PMID: 16524389 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A global function index (GFI) derived from tissue Doppler imaging (TDI) has been proposed to improve the diagnosis of hypertrophic cardiomyopathy (HCM). We aimed to evaluate the usefulness of this index in a large selected HCM population. METHODS: GFI =[E/Ea]/Sa, was calculated at mitral annulus lateral and septal borders in 164 HCM patients and in 40 healthy volunteers. Group comparisons and correlations between GFI and other variables were performed. RESULTS: Of the 164 patients, 69 (42%) had a peak gradient >30 mmHg in the left ventricle outflow tract (LVOT). GFI (lateral or septal) was not normally distributed. There were differences among controls, obstructive HCM, and nonobstructive HCM (P < 0.0001), but significant overlap of GFI values were observed between groups. GFI was correlated to septal thickness (r = 0.44; P < 0.0001), left atrial diameter (r = 0.52; P < 0.0001), and LVOT gradient (r = 0.58; P < 0.0001). CONCLUSION: In a selected HCM population, GFI was limited by its asymmetrical distribution and significant overlap of values between groups. Further studies are necessary to verify the reliability of GFI in the clinical practice and its position among other tissue Doppler indices. |
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Authors:
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Aloir Q Araujo; Edmundo Arteaga; Barbara M Ianni; Vera Maria C Salemi; Felix J A Ramires; Afonso Y Matsumoto; Fabio Fernandes; Charles Mady |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: 23 ISSN: 0742-2822 ISO Abbreviation: Echocardiography Publication Date: 2006 Mar |
Date Detail:
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Created Date: 2006-03-09 Completed Date: 2006-08-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: United States |
Other Details:
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Languages: eng Pagination: 197-201 Citation Subset: IM |
Affiliation:
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Heart Institute (INCOR), University of São Paulo Medical School, São Paulo, Brazil. aloirqueiroz@cardiol.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cardiomyopathy, Hypertrophic / physiopathology, ultrasonography* Case-Control Studies Cross-Sectional Studies Echocardiography, Doppler* Female Humans Male Middle Aged Retrospective Studies Statistics, Nonparametric |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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