Document Detail

Usefulness of a new perchloric acid treatment method to measure endotoxin in cerebrospinal fluid by the limulus test.
MedLine Citation:
PMID:  8109226     Owner:  NLM     Status:  MEDLINE    
The modernized limulus lysate assay on cerebrospinal fluid pretreated by the new perchloric acid (PCA) treatment was evaluated in one patient with Escherichia coli meningitis and four non-meningitis patients. The endotoxin (ET) concentration was much higher by the new PCA treatment than by the ordinary dilution method in the exacerbation phase of E. coli meningitis. The recovery rate of added ET also demonstrated the superiority of the new PCA treatment.
H Suda; K Inada; M Yoshida
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta paediatrica Japonica; Overseas edition     Volume:  35     ISSN:  0374-5600     ISO Abbreviation:  Acta Paediatr Jpn     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-03-22     Completed Date:  1994-03-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370357     Medline TA:  Acta Paediatr Jpn     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  496-9     Citation Subset:  IM    
Perinatal Medical Center, Morioka Red Cross Hospital, Japan.
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MeSH Terms
Endotoxins / cerebrospinal fluid*
Escherichia coli*
Limulus Test / methods*
Meningitis, Bacterial / cerebrospinal fluid,  diagnosis*
Perchloric Acid*
Reg. No./Substance:
0/Endotoxins; 7601-90-3/Perchloric Acid

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