Document Detail

Usefulness of massive oral nicorandil in a patient with variant angina refractory to conventional treatment.
MedLine Citation:
PMID:  12636235     Owner:  NLM     Status:  MEDLINE    
A 67-year-old man, who was previously diagnosed with vasospastic angina and treated with standard therapy, was admitted to our hospital because of recurrent chest pain refractory to sublingual nitroglycerin. Admission electrocardiography revealed ST segment elevation in II, III and aV(F), and his symptoms were relieved by intravenous bolus administration of nicorandil. He was diagnosed to have active variant angina, and remained symptomatic even after treatment with calcium antagonists and nitrates at optimal doses. Intravenous bolus administration of nicorandil was consistently effective to relieve his symptoms. Anginal attack was finally prevented by massive oral nicorandil in addition to conventional treatment.
Satoshi Kurisu; Ichiro Inoue; Takuji Kawagoe; Masaharu Ishihara; Yuji Shimatani; Kenji Nishioka; Shuji Nakamura; Takashi Umemura; Masashi Yoshida
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  42     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-03-14     Completed Date:  2003-06-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  163-7     Citation Subset:  IM    
Division of Cardiology, Hiroshima City Hospital, Hiroshima.
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MeSH Terms
Administration, Oral
Angina Pectoris, Variant / diagnosis*,  drug therapy*
Calcium Channel Blockers / therapeutic use
Coronary Angiography
Dose-Response Relationship, Drug
Follow-Up Studies
Infusions, Intravenous
Nicorandil / administration & dosage*
Nitroglycerin / therapeutic use
Severity of Illness Index
Treatment Outcome
Vasodilator Agents / administration & dosage*
Reg. No./Substance:
0/Calcium Channel Blockers; 0/Vasodilator Agents; 55-63-0/Nitroglycerin; 65141-46-0/Nicorandil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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