Document Detail

Usefulness of magnetocardiogram to detect unstable angina pectoris and non-ST elevation myocardial infarction.
MedLine Citation:
PMID:  19195500     Owner:  NLM     Status:  MEDLINE    
Electrophysiologic information as well as anatomic information to detect coronary artery disease is important for accurate diagnosis. A diagnostic tool that can detect patients with unstable angina pectoris (UAP) or non-ST elevation myocardial infarction (NSTEMI) with severe stenosis would be beneficial for patients and clinicians. Magnetocardiography has been recognized as a noncontact, noninvasive, fast tool to detect ischemic coronary artery disease and provide direct electrophysiologic information from the heart. In this study, 10 magnetocardiographic (MCG) parameters from 4 groups, including 185 young controls, 19 age-matched controls (AMCs), 110 patients with UAP, and 83 patients with NSTEMIs, were analyzed. A 64-channel MCG system in a magnetically shielded room was used. All 10 parameters showed significant differences (p <0.001) between controls and patients with NSTEMIs, and 6 parameters showed significant differences (p <0.01) between AMCs and patients with UAP. MCG parameters significantly increased when ischemic heart conditions worsened. Of the 10 parameters, the magnetic field map was among the easiest ways to detect the severity of coronary artery disease. Abnormal magnetic field maps were observed frequently with worsening ischemic coronary artery disease (70% of patients with UAP and 92.5% of those with NSTEMIs had abnormal maps). The combination of the binary boundaries of the 10 parameters had 96.4% sensitivity and 85% specificity to detect NSTEMI. In conclusion, the MCG parameters and magnetic field maps may detect UAP and NSTEMI easily when they are considered together.
Hyun Kyoon Lim; Hyukchan Kwon; Namsik Chung; Young-Guk Ko; Jin-Mok Kim; In-Seon Kim; Yong-Ki Park
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-12-25
Journal Detail:
Title:  The American journal of cardiology     Volume:  103     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-06     Completed Date:  2009-03-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  448-54     Citation Subset:  AIM; IM    
Korea Research Institute of Standards and Science, Daejeon, Korea.
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MeSH Terms
Angina, Unstable / diagnosis*
Case-Control Studies
Middle Aged
Myocardial Infarction / diagnosis*
Sensitivity and Specificity

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