| Usefulness of high functional capacity in patients with exercise-induced ST-depression to predict a negative result on exercise echocardiography and low prognostic risk. | |
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MedLine Citation:
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PMID: 18489930 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although exercise electrocardiography (ExECG) is commonly used to detect coronary artery disease, the diagnostic accuracy and reliability of positive (ischemic) results of ExECG in low- and intermediate-risk populations are limited. Accordingly, many patients with positive results of ExECG undergo secondary evaluation using noninvasive stress imaging such as exercise echocardiography. Functional capacity is a strong predictor of prognosis and, indirectly, of high-risk coronary artery disease. It was hypothesized that high functional capacity in patients with positive results of ExECG would predict (1) negative results on subsequent exercise echocardiography and (2) a low risk for late mortality. Results were analyzed in 104 consecutive patients (79 men, 25 women; mean age 49 years, range 27 to 76) referred for exercise echocardiography after positive results of ExECG with a treadmill workload of > or =10 METs. Late all-cause mortality was also determined in these patients. Exercise echocardiographic results were negative in 93% of patients (97 of 104; 92% of men [73 of 79] and 100% of women [25 of 25]) and positive in 7% (7 of 104). During a mean follow-up period of 7.2 +/- 1.9 years, there was 1 death. In conclusion, high functional capacity in patients with positive results of ExECG is associated with negative exercise echocardiographic results in most patients and very low late mortality. Patients with ischemic ST-segment response on ExECG who achieve workloads of > or =10 METs infrequently require additional noninvasive or invasive evaluation. |
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Authors:
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Amogh Bhat; Amish Desai; Ezra A Amsterdam |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-04-02 |
Journal Detail:
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Title: The American journal of cardiology Volume: 101 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-05-20 Completed Date: 2008-07-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1541-3 Citation Subset: AIM; IM |
Affiliation:
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Department of Internal Medicine, University of California, Davis, Medical Center, Sacramento, California, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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California
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epidemiology Coronary Disease / diagnosis*, epidemiology, physiopathology Disease Progression Echocardiography, Stress / methods* Electrocardiography* Exercise Test / adverse effects*, methods Exercise Tolerance / physiology* Female Follow-Up Studies Humans Incidence Male Middle Aged Predictive Value of Tests Prognosis Reproducibility of Results Retrospective Studies Risk Factors Survival Rate / trends |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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