| Usefulness of the mitral/aortic flow velocity integral ratio as a screening method to identify patients with hemodynamically significant mitral regurgitation. | |
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MedLine Citation:
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PMID: 12724652 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We sought to test the value of a simple Doppler index, the mitral/aortic flow velocity integral ratio (MAVIR), as a screening method to identify patients with hemodynamically significant mitral regurgitation (MR). METHODS: Included in the study were 91 patients (mean age 61 +/- 14 years; 54% men) with echocardiographically diagnosed MR. The cause was organic in 23 patients and ischemic/functional in 68. MR degree was assessed by 2 quantitative echocardiographic measures: the regurgitant fraction and the regurgitant orifice area. RESULTS: A good correlation was found between MAVIR and both regurgitant fraction (r = 0.75) and orifice (r = 0.60). When we divided patients into 3 groups on the basis of the regurgitant fraction, used as reference standard, MAVIR significantly increased in proportion to MR severity (0.7 +/- 0.1 for mild MR vs 1.1 +/- 0.2 for moderate and 1.4 +/- 0.3 for severe regurgitation; P <.0001). A ratio > 1 identified 28 of 30 patients with severe MR (regurgitant fraction > 60%), whereas all patients with mild MR (regurgitant fraction < 40%) had a ratio < 1. Using a regurgitant orifice >or= 40 mm(2) as threshold for severe MR, a significant difference in MAVIR was also present among patients who had severe MR compared with those having mild and moderate regurgitation (P <.0001). CONCLUSIONS: These findings suggest that MAVIR is a sensitive index, potentially widely applicable in clinical practice as a screening parameter for identifying patients with hemodynamically significant MR. |
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Authors:
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Luigi Ascione; Mario De Michele; Maria Accadia; Pio Francesco Tartaglia; Pasquale Guarini; Cosimo Sacra; Bernardino Tuccillo |
Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 16 ISSN: 0894-7317 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-01 Completed Date: 2003-08-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 437-41 Citation Subset: IM |
Affiliation:
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Division of Cardiology, S Maria di Loreto Hospital, Naples, Italy. lascio@tin.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Aortic Valve / physiopathology Blood Flow Velocity Child Echocardiography, Doppler, Color* Feasibility Studies Female Humans Male Middle Aged Mitral Valve / physiopathology Mitral Valve Insufficiency / physiopathology, ultrasonography* Prospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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