| Usefulness of endoscopic ultrasound in patients at high risk of choledocholithiasis. | |
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MedLine Citation:
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PMID: 16200174 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) has been considered the nonsurgical gold standard for the diagnosis and treatment of choledocholithiasis (CDL). Complications include a 0.1% to 1.3% mortality rate and a 5% to 19% morbidity rate, including a reported 1.8% to 6.7% incidence of postprocedure pancreatitis. Twenty-seven percent to 67% of ERCPs done for suspected choledocholithiasis ultimately have negative results. Endoscopic ultrasound (EUS) has been proposed as an alternate means of diagnosing choledocholithiasis that may eliminate the need for ERCP and its associated morbidities in certain patients. METHODS: Retrospective chart review identified 30 patients who underwent EUS with or without ERCP for suspected choledocholithiasis. Reports of all procedures performed were obtained and data were collected on all biliary abnormalities identified on both EUS and ERCP. RESULTS: Pancreaticobiliary abnormalities were identified in 27 of 30 patients (90%) at EUS. Most common diagnoses included CDL (n = 9, 30%), biliary sludge (n = 11, 37%), pancreatitis (n = 8, 27%), and cholelithiasis (n = 7, 23%). Subsequent ERCP was performed in 14 patients (47%). Indications included a diagnosis of CDL by EUS (n = 9) and abnormal liver function tests (n = 5). CDL was identified in 5 of 14 patients (36%), and microlithiasis/biliary sludge was identified in an additional 5 patients (36%). In 4 patients, CDL was identified by EUS but not by ERCP. ERCP did not identify any new cases of CDL after EUS: of 21 patients without evidence of CDL on EUS, none were subsequently shown to have CDL or to develop any complications related to common duct stones. CONCLUSIONS: EUS is an effective method of diagnosing CDL. It demonstrates both a high sensitivity and specificity for identifying common bile duct stones. Its use as a screening modality in patients suspected of having CDL may allow more selective use of ERCP. |
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Authors:
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George Dittrick; Jeffrey P Lamont; Joseph A Kuhn; Damien Mallat |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Proceedings (Baylor University. Medical Center) Volume: 18 ISSN: 0899-8280 ISO Abbreviation: Proc (Bayl Univ Med Cent) Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-10-03 Completed Date: 2005-10-20 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 9302033 Medline TA: Proc (Bayl Univ Med Cent) Country: United States |
Other Details:
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Languages: eng Pagination: 211-3 Citation Subset: - |
Affiliation:
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Department of Surgery, Baylor University Medical Center, Dallas, Texas, USA. |
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