| Usefulness of an elevated troponin-I in predicting clinical events in patients admitted with acute heart failure and acute coronary syndrome (from the RITZ-4 trial). | |
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MedLine Citation:
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PMID: 15165935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relation of cardiac troponin-I (cTnI) to clinical outcomes was examined in patients with decompensated heart failure and concomitant acute coronary syndrome enrolled into the Randomized Intravenous TeZosentan 4 (RITZ-4) study. RITZ-4 was a multicenter, randomized, double-blind, placebo-controlled trial of the endothelin receptor antagonist tezosentan in patients admitted with acute heart failure and concomitant acute coronary syndrome. One hundred ninety-two patients were enrolled in this study. Patients with baseline cTnI values were included in this analysis, and the relation between cTnI and the composite clinical primary end point of RITZ-4 was evaluated. |
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Authors:
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Wendy A Gattis; Christopher M O'Connor; Vic Hasselblad; Kirkwood F Adams; Isaac Kobrin; Mihai Gheorghiade |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of cardiology Volume: 93 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-05-28 Completed Date: 2004-06-25 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1436-7, A10 Citation Subset: AIM; IM |
Affiliation:
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Duke Clinical Research Institute, Duke University Medical Center, 2400 N. Pratt Street, Box 17969, Durham, NC 27710, USA. wendy.gattis@duke.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Coronary Disease / blood*, complications Female Heart Failure / blood*, complications Humans Male Multicenter Studies as Topic Pyridines / therapeutic use Randomized Controlled Trials as Topic Receptors, Endothelin / antagonists & inhibitors Retrospective Studies Risk Factors Tetrazoles / therapeutic use Troponin I / blood* Vasodilator Agents / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Pyridines; 0/Receptors, Endothelin; 0/Tetrazoles; 0/Troponin I; 0/Vasodilator Agents; 0/tezosentan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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