Document Detail

Usefulness of early dobutamine stress echocardiography for the assessment of risk of restenosis after percutaneous coronary interventions.
MedLine Citation:
PMID:  17436153     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The increasing role of percutaneous coronary interventions (PCI) in the treatment of coronary artery disease and relatively high restenosis rate following PCI require the introduction of available, easy to perform and cost-effective tests that would enable detection of restenosis after PTCA and identification of patients at particularly high risk of restenosis. AIM: To estimate the predictive value of early dobutamine stress echocardiography (DSE) for the assessment of risk of coronary restenosis. METHODS: Thirty-nine patients with a single coronary vessel disease after PCI were enrolled in this study. DSE was performed twice--2 to 3 days after the procedure and repeated after 8 to 12 months. All patients underwent coronary angiography after one-year follow-up. RESULTS: Data analysis of direct pre- and postprocedural echocardiography showed that the wall motion score index decreased significantly (p <0.0001), whereas ejection fraction increased significantly after the intervention when compared with baseline (p <0.0001). Restenosis was detected in 8 out of 10 subjects with positive DSE test and in 3 out of 29 subjects with negative DSE test. In a group of 11 patients with restenosis confirmed in the coronary angiography, one-year follow-up DSE was found positive in 9 patients (80% test sensitivity) but in two cases results were false negative. Negative test was observed in 27 out of 28 individuals without restenosis (90% test specificity). CONCLUSIONS: DSE is highly sensitive and specific in prediction and detection of restenosis after PCI. DSE performed early after PCI is safe.
Irmina Kossuth; Zdzisława Kornacewicz-Jach; Edyta Płońska; Andrzej Wojtarowicz; Jarosław Goracy; Krzysztof Przybycień; Maciej Lewandowski
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Kardiologia polska     Volume:  65     ISSN:  0022-9032     ISO Abbreviation:  Kardiol Pol     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-04-16     Completed Date:  2007-08-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376352     Medline TA:  Kardiol Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  254-9; discussion 260-1     Citation Subset:  IM    
Department of Cardiology, Pomeranian Medical University, Szczecin, Poland.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Angiography
Coronary Restenosis / radiography,  ultrasonography*
Coronary Stenosis / therapy*
Echocardiography, Stress*
Follow-Up Studies
Middle Aged
Postoperative Complications
Predictive Value of Tests
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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