Document Detail


Usefulness of contrast echocardiography for assessment of intracardiac masses.
MedLine Citation:
PMID:  19375671     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Conventional echocardiography is not a reliable method for characterizing tissue patterns of intracardiac masses.
AIMS: To assess the ability of contrast echocardiography to characterize intracardiac masses.
METHODS: Thirty-one consecutive patients with an intracardiac mass were included in this prospective study. All patients underwent conventional and contrast echocardiographic examinations. Analysis of characteristics by contrast agent allowed classification of intracardiac masses as follows: complete lack of enhancement, suggesting thrombus; partial and/or incomplete enhancement, suggesting myxoma; complete enhancement, suggesting intracardiac tumor. Tissue characteristics of intracardiac masses were also analyzed using at least one of the following techniques: cardiac magnetic resonance, pathology of intracardiac mass and/or mass resolved after anticoagulation during follow-up.
RESULTS: Using contrast echocardiography, an accurate diagnosis was made in all patients by an experienced investigator and in all patients except one (97%), by a physician trainee (p=0.31). Among patients with a history of tumor, echocardiography allowed accurate diagnosis of the nature of the mass in all patients; 50% of these patients presented with a secondary cardiac tumor and the others had a thrombus. Of the 14patients with a thrombus located in the left ventricle, 12 (86%) presented with left ventricular motion abnormalities using conventional echocardiography, whereas wall motion abnormalities were observed in all 14patients (100%) using contrast agent. In these patients, 91 and 99% of left ventricular segments were well visualized using conventional and contrast echocardiography, respectively (p<0.0001).
CONCLUSIONS: Contrast echocardiography may be useful for the tissue characterization of intracardiac masses.
Authors:
Nicolas Mansencal; Laure Revault-d'Allonnes; Jean-Pierre Pelage; Jean-Christian Farcot; Pascal Lacombe; Olivier Dubourg
Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2009-03-06
Journal Detail:
Title:  Archives of cardiovascular diseases     Volume:  102     ISSN:  1875-2136     ISO Abbreviation:  Arch Cardiovasc Dis     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-04-20     Completed Date:  2009-06-19     Revised Date:  2011-04-25    
Medline Journal Info:
Nlm Unique ID:  101465655     Medline TA:  Arch Cardiovasc Dis     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  177-83     Citation Subset:  IM    
Affiliation:
Pôle radiocardiovasculaire, centre de référence pour les maladies cardiaques heréditaires, hôpital Ambroise-Paré, Assistance publique-Hôpitaux de Paris, université de Versailles-Saint-Quentin (UVSQ), Boulogne, France. nicolas.mansencal@apr.aphp.fr
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Anticoagulants / therapeutic use
Biopsy
Contrast Media / diagnostic use*
Diagnosis, Differential
Echocardiography / methods*
Female
Heart Neoplasms / ultrasonography*
Humans
Magnetic Resonance Imaging
Male
Microbubbles
Middle Aged
Myocardial Contraction
Myxoma / ultrasonography*
Predictive Value of Tests
Prospective Studies
Thrombosis / drug therapy,  physiopathology,  ultrasonography*
Treatment Outcome
Ventricular Function, Left
Chemical
Reg. No./Substance:
0/Anticoagulants; 0/Contrast Media
Comments/Corrections
Comment In:
Arch Cardiovasc Dis. 2009 Mar;102(3):163-4   [PMID:  19375668 ]

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