Document Detail

Usefulness of continuous oxygen insufflation into trachea for management of upper airway obstruction during anesthesia.
MedLine Citation:
PMID:  10861147     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Severe complications associated with upper airway obstruction often occur during the perioperative period. Development of a simple and reliable technique for reversing the impaired airway patency may improve airway management. The purpose of the current study is to evaluate the usefulness of transtracheal oxygen insufflation (TTI) for management of upper airway obstruction during anesthesia and to explore the mechanisms of TTI in detail. METHODS: During propofol anesthesia in eight spontaneously breathing patients, the upper airway cross-sectional area and pressure-flow measurements during neck flexion with TTI were compared with those during triple airway maneuvers (TAM) without TTI. Blood gas analyses assessed efficacy of CO2 elimination during TTI in an additional nine patients. RESULTS: TTI achieved adequate PaCO2 and PaO2 levels equivalent to those during TAM. In addition to a significantly smaller cross-sectional area during TTI, the location and slope of the pressure-flow relation during TTI completely differed from those during TAM, indicating that upper airway resistance was much higher during TTI. Notably, minute ventilation during TTI was significantly smaller than that during TAM, suggesting reduced dead space or other mechanisms for CO2 elimination. CONCLUSIONS: TTI is capable of maintaining adequate blood gases through mechanisms different from those of conventional airway support in anesthetized subjects with upper airway obstruction.
J Okazaki; S Isono; A Tanaka; Y Tagaito; A R Schwartz; T Nishino
Related Documents :
18367017 - Obstructive sleep apnea and hypertension: mechanisms, evaluation, and management.
7251457 - A new method for computer-assisted determination of airways resistance.
9863997 - Effect of a novel pacap-27 analogue on muscarinic airway responsiveness in guinea-pigs ...
19940097 - The influence of end-expiratory lung volume on measurements of pharyngeal collapsibility.
9212117 - Intracoronary levosimendan enhances contractile function of stunned myocardium.
21868297 - Application of low-pressure negative pressure wound therapy to ischaemic wounds.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesiology     Volume:  93     ISSN:  0003-3022     ISO Abbreviation:  Anesthesiology     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-08-07     Completed Date:  2000-08-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1300217     Medline TA:  Anesthesiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  62-8     Citation Subset:  AIM; IM    
Chiba University School of Medicine, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Airway Obstruction / therapy*
Anesthesia, General*
Anesthetics, Intravenous
Blood Gas Analysis
Intraoperative Complications / therapy*
Middle Aged
Oxygen / administration & dosage*,  therapeutic use
Reg. No./Substance:
0/Anesthetics, Intravenous; 2078-54-8/Propofol; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Regulation of proprioceptive memory by subarachnoid regional anesthesia.
Next Document:  Correlation properties and complexity of perioperative RR-interval dynamics in coronary artery bypas...