Document Detail


Usefulness of FDG PET for assessment of early recurrent epithelial ovarian cancer.
MedLine Citation:
PMID:  12130439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of our study was to evaluate the diagnostic accuracy of FDG positron emission tomography (PET) in comparison with CT in detecting recurrent ovarian carcinoma and its ability to reveal small tumor recurrence. MATERIALS AND METHODS: We reviewed the records of 31 consecutive patients with pathologically proven epithelial carcinoma who underwent FDG PET 1 month before second-look surgery to assess recurrent tumor. Of these 31 patients, 21 patients also underwent CT 1 month before second-look surgery. The diagnostic accuracies of FDG PET (n = 31), CT (n = 21), and combined FDG PET and CT (n = 21) in detecting recurrent tumor were calculated and compared with each other using the Bennett's test in 21 patients who underwent both imaging studies. Detection rates of individual tumors relative to their sizes were compared between FDG PET and CT using the McNemar test. RESULTS: The sensitivity, specificity, and accuracy of FDG PET, CT, and combined FDG PET and CT for revealing recurrent ovarian cancer were 45.3%, 99.7%, 91.0%; 54.5%, 99.6%, 91.7%; 58.2%, 99.6%, 92.4%, respectively. We found no statistically significant difference in the diagnostic accuracy of FDG PET, CT, and combined FDG PET and CT (chi(2) < 5.991). Detection rates of tumor nodules found on CT were significantly greater than those on FDG PET when nodule size was 0.3-0.7 cm (p < 0.05). CONCLUSION: FDG PET did not improve the overall diagnostic accuracy in detecting recurrent ovarian carcinoma compared with CT. Rather, FDG PET was inferior to CT in its ability to reveal small-tumor recurrence.
Authors:
Song-Mee Cho; Hyun Kwon Ha; Jae Young Byun; Jae Mun Lee; Chan Joo Kim; Sung Eun Nam-Koong; Joon Mo Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  179     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-07-19     Completed Date:  2002-08-09     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  391-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, College of Medicine, The Catholic University of Korea, Seocho-Ku, Seoul, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Carcinoma / radiography,  radionuclide imaging*
Female
Fluorodeoxyglucose F18 / diagnostic use*
Humans
Middle Aged
Neoplasm Recurrence, Local / radiography,  radionuclide imaging*
Ovarian Neoplasms / radiography,  radionuclide imaging*
Predictive Value of Tests
Radiopharmaceuticals / diagnostic use*
Tomography, Emission-Computed*
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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