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Usefulness of F-18 FDG PET/CT in the Follow-up of POEMS Syndrome After Autologous Peripheral Blood Stem Cell Transplantation.
MedLine Citation:
PMID:  22228347     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We report a case of a patient with relapse of POEMS syndrome (peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasma proliferative disorder, skin changes) that occurred 6 years after an autologous peripheral blood stem cell transplantation. F-18 FDG PET/CT showed several hypermetabolic as well as nonhypermetabolic bone lesions. Based on these findings, the patient was referred for radiotherapy to the hypermetabolic bone lesions. After autologous peripheral blood stem cell transplantation, F-18 FDG PET/CT may play a pivotal role in detecting new bone lesions in patients with POEMS syndrome, which may be treated by a focalized radiotherapy and/or systemic therapy.
Authors:
Antonella Stefanelli; Giorgio Treglia; Lucia Leccisotti; Luca Laurenti; Marco Luigetti; Mario Sabatelli; Alessandro Giordano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  37     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  181-3     Citation Subset:  IM    
Affiliation:
From the *Institute of Nuclear Medicine, Catholic University of the Sacred Heart, Rome, Italy; †Institute of Hematology, Catholic University of the Sacred Heart, Rome, Italy; and ‡Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy.
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