Document Detail


Usefulness of CT angiography in diagnosing acute gastrointestinal bleeding: a meta-analysis.
MedLine Citation:
PMID:  20712058     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To analyze the accuracy of computed tomography (CT) angiography in the diagnosis of acute gastrointestinal (GI) bleeding.
METHODS: The MEDLINE, EMBASE, Cancerlit, Cochrane Library database, Sciencedirect, Springerlink and Scopus, from January 1995 to December 2009, were searched for studies evaluating the accuracy of CT angiography in diagnosing acute GI bleeding. Studies were included if they compared CT angiography to a reference standard of upper GI endoscopy, colonoscopy, angiography or surgery in the diagnosis of acute GI bleeding. Meta-analysis methods were used to pool sensitivity and specificity and to construct summary receiver-operating characteristic.
RESULTS: A total of 9 studies with 198 patients were included in this meta-analysis. Data were used to form 2 x 2 tables. CT angiography showed pooled sensitivity of 89% (95% CI: 82%-94%) and specificity of 85% (95% CI: 74%-92%), without showing significant heterogeneity (chi(2) = 12.5, P = 0.13) and (chi(2) = 22.95, P = 0.003), respectively. Summary receiver operating characteristic analysis showed an area under the curve of 0.9297.
CONCLUSION: CT angiography is an accurate, cost-effective tool in the diagnosis of acute GI bleeding and can show the precise location of bleeding, thereby directing further management.
Authors:
Lian-Ming Wu; Jian-Rong Xu; Yan Yin; Xin-Hua Qu
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  16     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-16     Completed Date:  2010-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  3957-63     Citation Subset:  IM    
Affiliation:
Department of Radiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, No. 1630 Dongfang Road, Pudong, Shanghai, China. xujianr@yeah.net.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Adult
Aged
Aged, 80 and over
Chi-Square Distribution
Child
Child, Preschool
Female
Gastrointestinal Hemorrhage / etiology,  radiography*
Humans
Male
Middle Aged
Predictive Value of Tests
ROC Curve
Sensitivity and Specificity
Tomography, X-Ray Computed*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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