| Use of vital capacity for cardiac failure risk estimation in persons with coronary disease and left ventricular hypertrophy. | |
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MedLine Citation:
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PMID: 8651087 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac failure is a common lethal outcome of coronary heart disease and left ventricular hypertrophy. The efficacy of forced vital capacity (FVC), measured biennially, in predicting the onset of cardiac failure was explored in 818 Framingham Study subjects with those predisposing conditions, among 324 developed cardiac failure. Among the men and women who had coronary disease or left ventricular hypertrophy, those with FVCs in the lower quartile were at substantially increased risk of developing cardiac failure. For men, comparing the lowest quartile with men whose FVCs were in the highest quartile (<2.7 L vs >5.6 L), the risk ratio was 1.8; for women with FVCs <1.7 L, the risk was 2.3 times those with FVCs of > or = 3.5L. The excess risk of cardiac failure imposed by a low FVC was similar in those with coronary disease and left ventricular hypertrophy. The simple FVC is an inexpensive and robust predictor of cardiac failure in persons predisposed by coronary disease or left ventricular hypertrophy. FVC determination should help identify candidates for cardiac failure needing echocardiographic examination for ventricular dysfunction. |
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Authors:
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W B Kannel; R B D'Agostino; H Silbershatz |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of cardiology Volume: 77 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1996-07-25 Completed Date: 1996-07-25 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1155-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Evans Memorial Research Foundation, Boston, Massachusetts, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cardiac Output, Low / complications, physiopathology* Coronary Disease / complications, physiopathology* Female Humans Hypertrophy, Left Ventricular / complications, physiopathology* Male Middle Aged Predictive Value of Tests Prospective Studies Vital Capacity* |
| Grant Support | |
ID/Acronym/Agency:
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N01-HV-52971/HV/NHLBI NIH HHS; N01-HV-92922/HV/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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